• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

应用蒙特卡罗代码 PENELOPE 对 192Ir 近距离放射治疗源进行剂量学特性描述。

Dosimetric characterization of an 192Ir brachytherapy source with the Monte Carlo code PENELOPE.

机构信息

Servicio de Radiofísica Hospitalaria, Hospital R.U. Carlos Haya, Av. Carlos Haya s/n, 29010 Málaga, Spain.

出版信息

Phys Med. 2010;26(3):132-9. doi: 10.1016/j.ejmp.2009.11.001. Epub 2010 Jan 14.

DOI:10.1016/j.ejmp.2009.11.001
PMID:20034828
Abstract

Monte Carlo calculations are highly spread and settled practice to calculate brachytherapy sources dosimetric parameters. In this study, recommendations of the AAPM TG-43U1 report have been followed to characterize the Varisource VS2000 (192)Ir high dose rate source, provided by Varian Oncology Systems. In order to obtain dosimetric parameters for this source, Monte Carlo calculations with PENELOPE code have been carried out. TG-43 formalism parameters have been presented, i.e., air kerma strength, dose rate constant, radial dose function and anisotropy function. Besides, a 2D Cartesian coordinates dose rate in water table has been calculated. These quantities are compared to this source reference data, finding results in good agreement with them. The data in the present study complement published data in the next aspects: (i) TG-43U1 recommendations are followed regarding to phantom ambient conditions and to uncertainty analysis, including statistical (type A) and systematic (type B) contributions; (ii) PENELOPE code is benchmarked for this source; (iii) Monte Carlo calculation methodology differs from that usually published in the way to estimate absorbed dose, leaving out the track-length estimator; (iv) the results of the present work comply with the most recent AAPM and ESTRO physics committee recommendations about Monte Carlo techniques, in regards to dose rate uncertainty values and established differences between our results and reference data. The results stated in this paper provide a complete parameter collection, which can be used for dosimetric calculations as well as a means of comparison with other datasets from this source.

摘要

蒙特卡罗计算是一种广泛应用于计算近距离治疗源剂量学参数的方法。在本研究中,遵循了 AAPM TG-43U1 报告的建议,对瓦里安肿瘤系统提供的 Varisource VS2000(192)Ir 高剂量率源进行了特征描述。为了获得该源的剂量学参数,我们使用 PENELoPE 代码进行了蒙特卡罗计算。给出了 TG-43 形式参数,即空气比释动能强度、剂量率常数、径向剂量函数和各向异性函数。此外,还计算了水模中二维笛卡尔坐标系的剂量率。将这些量与该源的参考数据进行了比较,发现结果非常吻合。本研究的数据在以下几个方面补充了已发表的数据:(i)在体模环境条件和不确定性分析方面遵循了 TG-43U1 建议,包括统计(A 类)和系统(B 类)贡献;(ii)对该源进行了 PENELoPE 代码基准测试;(iii)蒙特卡罗计算方法与通常发表的方法不同,在估计吸收剂量时省略了轨迹长度估计器;(iv)本工作的结果符合 AAPM 和 ESTRO 物理委员会关于蒙特卡罗技术的最新建议,在剂量率不确定性值和我们的结果与参考数据之间的差异方面。本文所述的结果提供了完整的参数集,可用于剂量计算,并可与该源的其他数据集进行比较。

相似文献

1
Dosimetric characterization of an 192Ir brachytherapy source with the Monte Carlo code PENELOPE.应用蒙特卡罗代码 PENELOPE 对 192Ir 近距离放射治疗源进行剂量学特性描述。
Phys Med. 2010;26(3):132-9. doi: 10.1016/j.ejmp.2009.11.001. Epub 2010 Jan 14.
2
Monte Carlo calculation of the TG-43 dosimetric parameters of a new BEBIG Ir-192 HDR source.新型BEBIG Ir-192高剂量率后装治疗源TG-43剂量学参数的蒙特卡罗计算
Radiother Oncol. 2005 Jul;76(1):79-85. doi: 10.1016/j.radonc.2005.06.016.
3
Evaluation of dosimetric parameters for various 192Ir brachytherapy sources under unbounded phantom geometry by Monte Carlo simulation.通过蒙特卡罗模拟评估无界体模几何条件下各种192Ir近距离放射治疗源的剂量学参数。
Med Dosim. 2007 Winter;32(4):305-15. doi: 10.1016/j.meddos.2007.03.005.
4
Monte Carlo dosimetric study of the BEBIG Co-60 HDR source.BEBIG Co-60高剂量率后装治疗源的蒙特卡罗剂量学研究
Phys Med Biol. 2005 Nov 7;50(21):N309-16. doi: 10.1088/0031-9155/50/21/N03. Epub 2005 Oct 12.
5
Study of the IsoAid ADVANTAGE (125)I brachytherapy source dosimetric parameters using Monte Carlo simulation.使用蒙特卡罗模拟对IsoAid ADVANTAGE (125)I近距离放射治疗源剂量学参数的研究。
Appl Radiat Isot. 2010 Jan;68(1):211-3. doi: 10.1016/j.apradiso.2009.08.007. Epub 2009 Aug 25.
6
Dosimetric characterization of the M-15 high-dose-rate Iridium-192 brachytherapy source using the AAPM and ESTRO formalism.使用美国医学物理学家协会(AAPM)和欧洲放射肿瘤学会(ESTRO)的形式体系对M-15高剂量率铱-192近距离放射治疗源进行剂量学表征。
J Appl Clin Med Phys. 2015 May 8;16(3):5270. doi: 10.1120/jacmp.v16i3.5270.
7
The IPEM code of practice for determination of the reference air kerma rate for HDR (192)Ir brachytherapy sources based on the NPL air kerma standard.基于 NPL 空气比释动能标准的 HDR(192)Ir 近距离治疗源参考空气比释动能率测定的 IPEM 实践规范。
Phys Med Biol. 2010 Jun 7;55(11):3145-59. doi: 10.1088/0031-9155/55/11/011. Epub 2010 May 17.
8
Dosimetric characterization of the (60)Co BEBIG Co0.A86 high dose rate brachytherapy source using PENELOPE.使用PENELOPE对(60)Co BEBIG Co0.A86高剂量率近距离放射治疗源进行剂量学表征。
Phys Med. 2014 Dec;30(8):960-7. doi: 10.1016/j.ejmp.2014.06.039. Epub 2014 Jul 19.
9
Monte Carlo and experimental characterization of the first AMIRS 103Pd brachytherapy source.首个AMIRS 103Pd近距离放射治疗源的蒙特卡罗模拟与实验表征
Appl Radiat Isot. 2008 Dec;66(12):1856-60. doi: 10.1016/j.apradiso.2008.06.007. Epub 2008 Jun 14.
10
A generic high-dose rate (192)Ir brachytherapy source for evaluation of model-based dose calculations beyond the TG-43 formalism.一种用于评估超越TG-43形式主义的基于模型剂量计算的通用高剂量率(192)铱近距离治疗源。
Med Phys. 2015 Jun;42(6):3048-61. doi: 10.1118/1.4921020.

引用本文的文献

1
Dosimetric investigation of a new high dose rate Ir brachytherapy source, IRAsource, by Monte Carlo method.用蒙特卡罗方法对一种新型高剂量率铱近距离治疗源IRAsource进行剂量学研究。
Rep Pract Oncol Radiother. 2020 Jan-Feb;25(1):139-145. doi: 10.1016/j.rpor.2019.12.022. Epub 2019 Dec 26.
2
Therapeutic analysis of high-dose-rate (192)Ir vaginal cuff brachytherapy for endometrial cancer using a cylindrical target volume model and varied cancer cell distributions.使用圆柱形靶区体积模型和不同癌细胞分布对子宫内膜癌进行高剂量率(192)铱阴道残端近距离放射治疗的疗效分析
Med Phys. 2016 Jan;43(1):483. doi: 10.1118/1.4939064.
3
Brachytherapy treatment planning commissioning: effect of the election of proper bibliography and finite size of TG-43 input data on standard treatments.
近距离放射治疗治疗计划的调试:选择合适的参考文献及TG-43输入数据的有限大小对标准治疗的影响。
J Appl Clin Med Phys. 2015 Jul 8;16(4):3-17. doi: 10.1120/jacmp.v16i4.4730.
4
Monte Carlo characterization of 169Yb as a high-dose-rate source for brachytherapy application by FLUKA code.通过 FLUKA 代码对 169Yb 进行 Monte Carlo 特征描述,作为近距离治疗应用的高剂量率源。
J Appl Clin Med Phys. 2013 Jul 8;14(4):4298. doi: 10.1120/jacmp.v14i4.4298.