Graduate School of Sport Sciences, Waseda University, Saitama, Japan.
J Physiol Anthropol. 2011;30(4):133-9. doi: 10.2114/jpa2.30.133.
We examined whether cardiorespiratory fitness (maximal oxygen uptake, VO(2)max) and muscular strength (grip strength) are associated with individual and clustered metabolic risk factors independently of abdominal adiposity in Japanese men (n=110) and women (n=110) aged 20-69 years. Blood pressure, triglycerides (TG), HDL cholesterol, and fasting plasma glucose (FPG) were assessed and metabolic risk score was calculated, which is the sum of the z scores for each individual risk factor. Waist circumference was measured and the area of visceral fat was assessed by MRI. Multiple linear regression analysis revealed that VO(2)max was inversely associated with TG in men (p<0.05) and grip strength was negatively associated with FPG and metabolic risk score in women (p<0.001 and p<0.05, respectively), independently of waist circumference. Adjusting for visceral fat instead of waist circumference, similar results were obtained in women (p<0.01 and p<0.05, respectively), but the association between VO(2)max and TG in men was attenuated to nonsignificant. This cross-sectional study demonstrates that muscular strength is inversely associated with plasma glucose levels and clustered metabolic risk factors independently of abdominal adiposity in Japanese women, but not in men.
我们研究了心肺功能（最大摄氧量，VO2max）和肌肉力量（握力）是否与腹部肥胖以外的个体和聚集代谢风险因素相关，纳入了 20-69 岁的日本男性（n=110）和女性（n=110）。评估了血压、甘油三酯（TG）、高密度脂蛋白胆固醇和空腹血糖（FPG），并计算了代谢风险评分，即每个个体风险因素的 z 分数之和。测量了腰围，并通过 MRI 评估了内脏脂肪面积。多元线性回归分析显示，男性的 VO2max 与 TG 呈负相关（p<0.05），女性的握力与 FPG 和代谢风险评分呈负相关（p<0.001 和 p<0.05，分别），与腰围独立。在女性中，用内脏脂肪代替腰围进行调整，得到了类似的结果（p<0.01 和 p<0.05，分别），但男性 VO2max 与 TG 之间的关联减弱至无统计学意义。这项横断面研究表明，肌肉力量与日本女性的血糖水平和聚集的代谢风险因素呈负相关，与腹部肥胖无关，但在男性中则没有这种关联。
