Jurca Radim, Lamonte Michael J, Church Timothy S, Earnest Conrad P, Fitzgerald Shannon J, Barlow Carolyn E, Jordan Alexander N, Kampert James B, Blair Steven N
The Cooper Institute, Dallas, TX 75230, USA.
Med Sci Sports Exerc. 2004 Aug;36(8):1301-7. doi: 10.1249/01.mss.0000135780.88930.a9.
To examine the associations for muscular strength and cardiorespiratory fitness with the prevalence of metabolic syndrome among men.
Participants were 8570 men (20-75 yr) for whom an age-specific muscular strength score was computed by combining the body weight adjusted one-repetition maximum measures for the leg press and the bench press. Cardiorespiratory fitness was quantified by age-specific maximal treadmill exercise test time.
Separate age and smoking adjusted logistic regression models revealed a graded inverse association for metabolic syndrome prevalence with muscular strength (beta = -0.37, P < 0.0001) and cardiorespiratory fitness (beta = -1.2, P < 0.0001). The association between strength and metabolic syndrome was attenuated (beta = -0.08, P < 0.01) when further adjusted for cardiorespiratory fitness. The association between cardiorespiratory fitness and metabolic syndrome was unchanged (beta = -1.2, P < 0.0001) after adjusting for strength. Muscular strength added to the protective effect of fitness among men with low (P trend = 0.0002) and moderate (P trend < 0.0001) fitness levels. Among normal weight (BMI < 25), overweight (BMI 25-30), and obese (BMI >or= 30) men, respectively, being strong and fit was associated with lower odds (73%, 69%, and 62% respectively, P < 0.0001) of having prevalent metabolic syndrome.
Muscular strength and cardiorespiratory fitness have independent and joint inverse associations with metabolic syndrome prevalence.
研究男性肌肉力量和心肺适能与代谢综合征患病率之间的关联。
研究对象为8570名年龄在20 - 75岁之间的男性，通过结合体重调整后的腿部推举和卧推一次重复最大重量测量值，计算出特定年龄的肌肉力量得分。心肺适能通过特定年龄的最大跑步机运动测试时间来量化。
分别调整年龄和吸烟因素后的逻辑回归模型显示，代谢综合征患病率与肌肉力量（β = -0.37，P < 0.0001）和心肺适能（β = -1.2，P < 0.0001）呈分级负相关。在进一步调整心肺适能后，力量与代谢综合征之间的关联减弱（β = -0.08，P < 0.01）。调整力量因素后，心肺适能与代谢综合征之间的关联未改变（β = -1.2，P < 0.0001）。在低（P趋势 = 0.0002）和中等（P趋势 < 0.0001）适能水平的男性中，肌肉力量增强了适能的保护作用。在正常体重（BMI < 25）、超重（BMI 25 - 30）和肥胖（BMI≥30）男性中，强壮且适能分别与较低（分别为73%、69%和62%，P < 0.0001）的代谢综合征患病率相关。
肌肉力量和心肺适能与代谢综合征患病率存在独立且共同的负相关。
