Antoniou G, Antoniou S
Regional Vascular Unit, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.
Int Angiol. 2011 Oct;30(5):481-7.
To evaluate the published outcomes of endovascular stent graft repair of renal artery aneurysms.
The English literature was systematically searched using the MEDLINE electronic database up to April 2010. All reports of endovascular stent graft repair of renal artery aneurysms were considered. The primary outcome measures were technical success and perioperative, 30-day and overall morbidity and mortality.
Data for the final analysis were extracted from 20 papers reporting on endovascular stent graft repair of 22 aneurysms in 21 patients. Elective repair was performed in 20 cases (91%), whereas 2 patients (9%) underwent an endovascular repair of a ruptured aneurysm. The technical success rate was 91% (20/22). Neither perioperative/30-day mortality nor significant perioperative morbidity was noticed in this study cohort. Minor perioperative complications developed 6 patients (27%), and were most commonly associated with occlusion of a side branch vessel resulting in segmental infarction of the kidney. None of the patients developed renal impairment. During a mean follow up of 8 months, no patients developed aneurysm-related complications requiring revision.
Endovascular stent graft repair of renal artery aneurysms is reported to be a safe and effective treatment option, with good immediate and short-term results. However, no long-term data exists and larger series are required to draw solid conclusions regarding the outcomes of this method.
评估肾动脉动脉瘤血管内支架移植物修复术已发表的治疗结果。
利用MEDLINE电子数据库对截至2010年4月的英文文献进行系统检索。纳入所有肾动脉动脉瘤血管内支架移植物修复术的报告。主要观察指标为技术成功率、围手术期、30天及总体发病率和死亡率。
最终分析的数据来自20篇报告,涉及21例患者的22个动脉瘤的血管内支架移植物修复术。20例(91%)进行了择期修复,而2例(9%)对破裂动脉瘤进行了血管内修复。技术成功率为91%(20/22)。本研究队列中未观察到围手术期/30天死亡率及显著的围手术期发病率。6例患者(27%)出现轻微围手术期并发症,最常见的是与侧支血管闭塞相关,导致肾节段性梗死。所有患者均未出现肾功能损害。在平均8个月的随访期间,无患者出现需要翻修的动脉瘤相关并发症。
据报道,肾动脉动脉瘤血管内支架移植物修复术是一种安全有效的治疗选择,近期和短期效果良好。然而,目前尚无长期数据,需要更大规模的系列研究才能就该方法的治疗结果得出确凿结论。