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口腔癌危险因素评估。

Evaluation of risk factors of oral cancer.

作者信息

Ekramuddaula F M, Siddique B H, Islam M R, Kabir M S, Alam M S

机构信息

Department of Otolaryngology, Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka, Bangladesh.

出版信息

Mymensingh Med J. 2011 Jul;20(3):412-8.

Abstract

This cross sectional study was done for the evaluation of the risk factors of oral cancer. This study was carried out in the department of Otolaryngology-Head & Neck Surgery of Bangabandhu Sheikh Mujib Medical University and Dhaka Medical College Hospital, Dhaka, Bangladesh. A total of 90 consecutive patients with oral squamous cell carcinoma (OSCC) were studied in Otolaryngology department of BSMMU and DMCH from January 2003 to December 2005. A questionnaire was used for data collection from careful history taking, clinical examination and investigations. About 71.1% were habituated with betel quid chewing, 36.7% were habituated with smoking but among 23.3 % also betel quid chewer in addition. None of the patient was found to be habituated with alcohol consumption. Majority of the patients of OSCC were malnourished, of which female were more in number, and it was found that nutritional status was significantly associated with sex. Odds ratio (OD) showed that malnutrition was positively associated with female subjects. Also it was found that 69.01% betel quid chewer was malnourished and nutritional status was significantly associated with chewing and smoking habit. Betel quid chewing, smoking and malnutrition is important risk factor of oral cancer.

摘要

本横断面研究旨在评估口腔癌的危险因素。该研究在孟加拉国达卡的班加班杜·谢赫·穆吉布医科大学和达卡医学院医院的耳鼻咽喉-头颈外科进行。2003年1月至2005年12月期间,在BSMMU和DMCH的耳鼻咽喉科对90例连续的口腔鳞状细胞癌(OSCC)患者进行了研究。通过仔细的病史采集、临床检查和调查,使用问卷进行数据收集。约71.1%的患者有嚼槟榔习惯,36.7%的患者有吸烟习惯,但其中23.3%的患者同时也嚼槟榔。未发现有患者有饮酒习惯。大多数OSCC患者营养不良,其中女性患者数量更多,且发现营养状况与性别显著相关。比值比(OD)显示营养不良与女性受试者呈正相关。还发现69.01%的嚼槟榔者营养不良,营养状况与咀嚼和吸烟习惯显著相关。嚼槟榔、吸烟和营养不良是口腔癌的重要危险因素。

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