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失眠亚型与巴西社区居住的老年人群日间过度嗜睡的关系。

Insomnia subtypes and their relationship to excessive daytime sleepiness in Brazilian community-dwelling older adults.

机构信息

Psychiatry Residency Programme - Psychopharmacology Course, Social Security Institute of the Civil Servants of Minas Gerais, Belo Horizonte, Brazil.

出版信息

Sleep. 2011 Aug 1;34(8):1111-7. doi: 10.5665/SLEEP.1172.

Abstract

STUDY OBJECTIVES

To investigate the association between different types of insomnia as exposures and excessive daytime sleepiness (EDS) as a binary outcome in older Brazilian residents.

DESIGN

The baseline examination of the Bambuí Health and Ageing Study (BHAS), which is an ongoing population-based prospective cohort study of older adults.

SETTING

Bambuí (15,000 inhabitants), a city in the State of Minas Gerais, Southeast Brazil

PARTICIPANTS

All residents aged ≥ 60 years were eligible to take part in the BHAS baseline. Of 1742 residents identified who were ≥ 60 years, 1606 (92.2%) were interviewed and received comprehensive examinations of health status.

INTERVENTIONS

None.

MEASUREMENTS AND RESULTS

EDS was defined as the presence of sleepiness ≥ 3 times per week in the last month, causing any interference in usual activities. All insomnia subtypes were significantly associated with EDS in unadjusted analyses, and these associations were only modestly altered after adjusting incrementally for the other covariates. In a final model, the 3 insomnia subtypes were entered into a fully adjusted model simultaneously to investigate mutual independence, giving prevalence ratios of 1.63 (95% CI 1.14-2.31) for initial insomnia, 2.13 (95% CI 1.48-3.07) for middle insomnia, and 1.36 (95% CI 0.94-1.96) for terminal insomnia. The population attributable fractions for initial, middle, and terminal insomnia on prevalence of EDS were 17.6%, 32.9%, and 9.7%, respectively.

CONCLUSIONS

Middle insomnia emerged as the insomnia subtype most strongly associated with EDS. Further research is required to clarify causal pathways underlying this cross-sectional association.

摘要

研究目的

调查不同类型的失眠(作为暴露因素)与巴西老年居民的日间嗜睡(EDS)(作为二分类结局)之间的关联。

设计

本研究是一项正在进行的、以老年人为基础的前瞻性队列研究——班比乌健康与衰老研究(BHAS)的基线检查。

地点

巴西东南部米纳斯吉拉斯州的班比乌(人口 15000)。

参与者

所有年龄≥60 岁的居民都有资格参加 BHAS 的基线研究。在确定的 1742 名≥60 岁的居民中,有 1606 名(92.2%)接受了采访并接受了健康状况的全面检查。

干预措施

无。

测量和结果

EDS 定义为过去 1 个月内每周≥3 次出现困倦,导致日常活动受到任何干扰。在未调整的分析中,所有失眠亚型与 EDS 均显著相关,这些关联在逐步调整其他协变量后仅略有改变。在最终模型中,将 3 种失眠亚型同时纳入完全调整的模型中以调查相互独立性,得出初始失眠的流行率比为 1.63(95%可信区间 1.14-2.31),中期失眠为 2.13(95%可信区间 1.48-3.07),终末期失眠为 1.36(95%可信区间 0.94-1.96)。初始、中期和终末期失眠对 EDS 流行率的人群归因分数分别为 17.6%、32.9%和 9.7%。

结论

中期失眠是与 EDS 关联最强的失眠亚型。需要进一步的研究来阐明这种横断面关联的因果途径。

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