Vlasov A P, Loginova O V, Vasil'ev V V, Vlasova T I, Shibitov V A, Kazaeva T N, Matveeva M V
Eksp Klin Farmakol. 2011;74(5):40-2.
It is found that the drug remaxol, which possesses antioxidant and antihypoxant properties, is also highly effective in correction of metabolism disorders in the kidneys with peritoneal endotoxicosis. The high neuroprotective effect of remaxol is related to its ability to correct the lipid metabolism violated by hypoxia phenomena in tissues, to decrease peroxidation of lipids and activity of phospholipase A2, and to recover intrinsic antioxidant potential of cellular structures of the kidney.
研究发现，具有抗氧化和抗缺氧特性的瑞马索药物在纠正腹膜内毒素血症时肾脏的代谢紊乱方面也非常有效。瑞马索的高神经保护作用与其纠正组织中因缺氧现象而受损的脂质代谢、降低脂质过氧化和磷脂酶A2活性以及恢复肾脏细胞结构的内在抗氧化潜力的能力有关。
