Department of Chemistry, Faculty of Science, Shahid Beheshti University, G.C., Tehran, Iran.
Nat Prod Res. 2012;26(2):146-51. doi: 10.1080/14786419.2010.534992. Epub 2011 Aug 2.
The chemical composition of the essential oil obtained from the aerial parts of Betonica grandiflora Willd., growing wild in Iran, was analysed by gas chromatography-mass spectrometry for the first time. Overall, 40 volatile components were identified on the basis of their mass spectra characteristics and retention indices in which ledol (21.8%), myrtenyl acetate (21.7%), eudesm-7(11)-en-4-ol (6.5%), trans-caryophyllene (5.5%), α-bisabolol (4.9%) and isolongifolol (4.5%) were the major constituents. Oxygenated sesquiterpenes, monoterpene hydrocarbons and sesquiterpene hydrocarbons were the main groups of compounds with 45.6%, 23.1% and 18.4%, respectively. The oil was moderately active against Bacillus subtilis and Staphylococcus aureus and inactive against Enterococcus faecalis and Klebsiella pneumoniae.
首次采用气相色谱-质谱联用技术分析了伊朗野生大贝母地上部分的精油的化学成分。基于质谱特征和保留指数，共鉴定出 40 种挥发性成分，其中，莱菔萜醇（21.8%）、桃金娘烯醇乙酸酯（21.7%）、桉叶-7(11)-烯-4-醇（6.5%）、反式石竹烯（5.5%）、α- 姜黄烯（4.9%）和异长叶烯（4.5%）为主要成分。含氧倍半萜、单萜烃和倍半萜烃分别为主要化合物组，占比分别为 45.6%、23.1%和 18.4%。该精油对枯草芽孢杆菌和金黄色葡萄球菌具有中度活性，对粪肠球菌和肺炎克雷伯菌无活性。
