Department of Molecular Microbiology and Immunology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Malar J. 2011 Aug 3;10:220. doi: 10.1186/1475-2875-10-220.
Malaria in the 21st century is showing signs of declining over much of its distribution, including several countries in Africa where previously this was not thought to be feasible. Yet for the most part the strategies to attack the infection are similar to those of the 1950s. Three major Journals have recently drawn attention to the situation, stressing the importance of research, describing the successes and defining semantics related to control. But there is a need to stress the importance of local sustainability, and consider somewhat urgently how individual endemic countries can plan and implement the programmes that are currently financed, for the most part, by donor institutions. On an immediate basis research should be more focused on a data driven approach to control. This will entail new thinking on the role of local infrastructure and in training of local scientists in local universities in epidemiology and field malariology so that expanded control programmes can become operational. Donor agencies should encourage and facilitate development of career opportunities for such personnel so that local expertise is available to contribute appropriately.
21 世纪，疟疾在其分布的大部分地区呈下降趋势，包括非洲的几个此前被认为不可能实现这一目标的国家。然而，在大多数情况下，对抗感染的策略与 20 世纪 50 年代的策略相似。最近，三家主要期刊引起了人们对这一情况的关注，强调了研究的重要性，描述了成功之处，并定义了与控制相关的语义。但是，有必要强调地方可持续性的重要性，并考虑一下，在目前由捐助机构为大部分提供资金的情况下，个别流行国家如何规划和实施这些方案。在当前阶段，研究应该更加注重基于数据的控制方法。这将需要对地方基础设施的作用以及在地方大学中培训地方流行病学家和实地疟疾学家的作用进行新的思考，以便扩大控制方案能够付诸实施。捐助机构应鼓励和促进此类人员职业机会的发展，以便当地专门知识能够得到适当的利用。
