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乌干达疟疾:消除疟疾道路上的挑战。二、前进的道路。

Malaria in Uganda: challenges to control on the long road to elimination. II. The path forward.

机构信息

Infectious Diseases Research Collaboration, Kampala, Uganda.

出版信息

Acta Trop. 2012 Mar;121(3):196-201. doi: 10.1016/j.actatropica.2011.06.013. Epub 2011 Jul 2.

Abstract

In the recent past there have been several reports of successes in malaria control, leading some public health experts to conclude that Africa is witnessing an epidemiological transition, from an era of failed malaria control to progression from successful control to elimination. Successes in control have been attributed to increased international donor support leading to increased intervention coverage. However, these changes are not uniform across Africa. In Uganda, where baseline transmission is very high and intervention coverage not yet to scale, the malaria burden is not declining and has even likely increased in the last decade. In this article we present perspectives for the future for Uganda and other malaria endemic countries with high baseline transmission intensity and significant health system challenges. For these high burden areas, malaria elimination is currently not feasible, and early elimination programs are inappropriate, as they would further fragment already fragmented and inefficient malaria control systems. Rather, health impacts will be maximized by aiming to achieve universal coverage of proven interventions in the context of a strengthened health system.

摘要

在最近的过去,有几项疟疾控制成功的报告,这使得一些公共卫生专家得出结论,非洲正在经历从疟疾控制失败的时代向成功控制并逐步消除疟疾的转变。控制工作的成功归因于国际捐助者的支持增加,导致干预措施的覆盖面扩大。然而,这些变化在非洲并非一致。在乌干达,基线传播率非常高,干预措施的覆盖面尚未达到规模,疟疾负担并未下降,甚至在过去十年中可能有所增加。在本文中,我们为乌干达和其他基线传播强度高且卫生系统面临重大挑战的疟疾流行国家提出了未来的观点。对于这些高负担地区,目前消除疟疾是不可行的,早期消除计划也不合适,因为它们会进一步使已经支离破碎和低效的疟疾控制系统进一步碎片化。相反,通过在加强卫生系统的背景下,实现经证实的干预措施的普遍覆盖,将最大限度地提高健康影响。

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