Rossi S, Fornari F, Pathies C, Buscarini L
Divisione di Medicina, Ospedale Civile di Piacenza, Italy.
Tumori. 1990 Feb 28;76(1):54-7. doi: 10.1177/030089169007600114.
We evaluated the type, dimension and histopathological evolution of thermal lesions induced in guinea pig and pig liver by radiofrequency electrode needles at various temperatures for different exposure times. The greatest useful necrosis volume was induced by a needle of 1.1 mm diameter and exposed Up 10 mm long at 90 degrees C and 120 seconds exposure time. It was an ellipsoid with the biggest diameter of about 14 mm diameter and length of about 18 mm. It seems possible that liver tumors of not more than 20 mm diameter in patients without surgical prospects could be destroyed, ultrasonography guiding the needle into the tumor and using the temperature and exposure time mentioned above.
我们评估了不同温度下，使用射频电极针在豚鼠和猪肝中诱导热损伤的类型、大小及组织病理学演变情况，观察了不同暴露时间的影响。直径1.1毫米、暴露长度达10毫米的针，在90摄氏度下暴露120秒时，可诱导出最大的有效坏死体积。坏死区域呈椭圆形，最大直径约14毫米，长度约18毫米。对于无手术指征、直径不超过20毫米的肝肿瘤患者，在超声引导下将针插入肿瘤，并采用上述温度和暴露时间，似乎有可能破坏肿瘤。
