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miRNAs in the spotlight: Understanding cancer gene dependency.

作者信息

Croce Carlo M

机构信息

Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University School of Medicine, Columbus, Ohio, USA.

出版信息

Nat Med. 2011 Aug 4;17(8):935-6. doi: 10.1038/nm0811-935.

DOI:10.1038/nm0811-935
PMID:21818092
Abstract
摘要

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Multicenter independent assessment of outcomes in chronic myeloid leukemia patients treated with imatinib.多中心独立评估伊马替尼治疗慢性髓性白血病患者的结局。
J Natl Cancer Inst. 2011 Apr 6;103(7):553-61. doi: 10.1093/jnci/djr060. Epub 2011 Mar 21.
2
OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma.在 miRNA-21 诱导的前 B 细胞淋巴瘤的体内模型中存在 oncomiR 成瘾。
Nature. 2010 Sep 2;467(7311):86-90. doi: 10.1038/nature09284. Epub 2010 Aug 8.
3
Oncogenes and cancer.癌基因与癌症
PLoS Comput Biol. 2022 Aug 11;18(8):e1009100. doi: 10.1371/journal.pcbi.1009100. eCollection 2022 Aug.
4
MicroRNA-106a suppresses prostate cancer proliferation, migration and invasion by targeting tumor-derived IL-8.微小RNA-106a通过靶向肿瘤源性白细胞介素-8抑制前列腺癌的增殖、迁移和侵袭。
Transl Cancer Res. 2020 May;9(5):3507-3517. doi: 10.21037/tcr.2020.03.70.
5
Endogenous and artificial miRNAs explore a rich variety of conformations: a potential relationship between secondary structure and biological functionality.内源性和人工 microRNA 探索了丰富多样的构象：二级结构与生物学功能之间的潜在关系。
Sci Rep. 2020 Jan 16;10(1):453. doi: 10.1038/s41598-019-57289-8.
6
Ionizing radiation-induced growth in soft agar is associated with miR-21 upregulation in wild-type and DNA double strand break repair deficient cells.电离辐射诱导软琼脂生长与野生型和 DNA 双链断裂修复缺陷细胞中 miR-21 的上调有关。
DNA Repair (Amst). 2019 Jun;78:37-44. doi: 10.1016/j.dnarep.2019.03.012. Epub 2019 Mar 23.
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miR-21-mediated Radioresistance Occurs via Promoting Repair of DNA Double Strand Breaks.微小RNA-21介导的放射抗性通过促进DNA双链断裂的修复而发生。
J Biol Chem. 2017 Feb 24;292(8):3531-3540. doi: 10.1074/jbc.M116.772392. Epub 2017 Jan 17.
8
MicroRNA-103 promotes tumor growth and metastasis in colorectal cancer by directly targeting LATS2.微小RNA-103通过直接靶向大肿瘤抑制因子2促进结直肠癌的肿瘤生长和转移。
Oncol Lett. 2016 Sep;12(3):2194-2200. doi: 10.3892/ol.2016.4814. Epub 2016 Jul 5.
9
MiR-449a exerts tumor-suppressive functions in human glioblastoma by targeting Myc-associated zinc-finger protein.微小RNA-449a通过靶向Myc相关锌指蛋白在人类胶质母细胞瘤中发挥肿瘤抑制功能。
Mol Oncol. 2015 Mar;9(3):640-56. doi: 10.1016/j.molonc.2014.11.003. Epub 2014 Nov 20.
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Oncogenic miR-20a and miR-106a enhance the invasiveness of human glioma stem cells by directly targeting TIMP-2.致癌 miRNA-20a 和 miRNA-106a 通过直接靶向 TIMP-2 增强人神经胶质瘤干细胞的侵袭性。
Oncogene. 2015 Mar 12;34(11):1407-19. doi: 10.1038/onc.2014.75. Epub 2014 Apr 7.
N Engl J Med. 2008 Jan 31;358(5):502-11. doi: 10.1056/NEJMra072367.
4
MicroRNA signatures in human cancers.人类癌症中的微小RNA特征
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Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice.E（μ）-miR155转基因小鼠中的前B细胞增殖与淋巴细胞白血病/高级别淋巴瘤
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