Department of Entomology, China Agricultural University, 2 Yuanmingyuan West Road, Haidian District, Beijing 100193, People's Republic of China.
J Agric Food Chem. 2011 Sep 28;59(18):9910-5. doi: 10.1021/jf202266n. Epub 2011 Aug 29.
The screening for bioactive principles from several Chinese medicinal herbs showed that the essential oil of Cymbopogon distans aerial parts possessed strong repellency against the booklouse, Liposcelis bostrychophila , and the red flour beetle, Tribolium castaneum . A total of 36 components of the essential oil were identified by GC and GC-MS. trans-Geraniol (16.54%), (R)-citronellal (15.44%), (+)-citronellol (11.51%), and α-elemol (9.06%) were the main components of the essential oil followed by β-eudesmol (5.71%) and (+)-limonene (5.05%). From the essential oil, four monoterpenes were isolated by bioassay-guided fractionation. The compounds were identified as limonene, citronellol, citronellal, and trans-geraniol. Geraniol and citronellol were strongly repellent against the booklouse, L. bostrychophila, whereas citronellal and limonene exhibited weak repellency against the booklouse. Geraniol and citronellol exhibited comparable repellency against the booklouse relative to the positive control, DEET. Moreover, geraniol and citronellol exhibited stronger repellency against the red flour beetle than DEET, whereas the two other compounds showed the same level of repellency against the red flour beetle compared with DEET.
从几种中药中筛选生物活性成分的结果表明,香茅草地上部分的精油对书虱(Liposcelis bostrychophila)和赤拟谷盗(Tribolium castaneum)具有很强的驱避作用。通过 GC 和 GC-MS 共鉴定出精油中的 36 种成分。反式香叶醇(16.54%)、(R)-香茅醛(15.44%)、(+)-香茅醇(11.51%)和α-依兰油醇(9.06%)是精油的主要成分,其次是β-桉叶醇(5.71%)和(+)-柠檬烯(5.05%)。通过生物活性导向分离从精油中分离出四种单萜。这些化合物被鉴定为柠檬烯、香茅醇、香茅醛和反式香叶醇。香叶醇和香茅醇对书虱具有强烈的驱避作用,而香茅醛和柠檬烯对书虱的驱避作用较弱。香叶醇和香茅醇对书虱的驱避作用与阳性对照 DEET 相当。此外,香叶醇和香茅醇对赤拟谷盗的驱避作用强于 DEET,而另外两种化合物对赤拟谷盗的驱避作用与 DEET 相当。