Department of Psychology, Human Psychophysiology Laboratory, Wheeling Jesuit University, Wheeling, WV 26003, USA.
Am J Rhinol Allergy. 2011 Jul-Aug;25(4):249-51. doi: 10.2500/ajra.2011.25.3621.
Several nasal dilator devices designed to stent the anterior nasal airway to increase peak nasal inspiratory flow (PNIF) currently exist; however, comparisons of such devices are limited. This study was designed to compare the efficacy of two different nasal dilator devices, an internal device (Max-Air Nose Cones; Sanostec Corp., Beverly Farms, MA) and an external device (Breathe Right nasal strip; GlaxoSmithKline, Brentford, Middlesex, U.K.) on stenting of the anterior nasal airway to maximize PNIF.
Repeated measurements of PNIF were obtained in 30 individuals noting complaints of sleep-disordered breathing due to nasal breathing discomfort and nasal airway obstruction, both with and without the two different nasal dilator devices.
A one-within analysis of variance (ANOVA) was performed among the three conditions (control, Max-Air Nose Cones, and Breathe Right nasal strip), and a statistically significant effect was found (F[2,58] = 298.13; p< 0.00001). Tukey post hoc contrasts revealed that the control condition PNIF (66.07 L/min) was significantly lower than both the Max-Air Nose Cones (138.73 L/min) and the Breathe Right nasal strip (102.17 L/min) conditions. The Max-Air Nose Cone increased inspiratory airflow by 73 L/min, or a 110% improvement over baseline. In addition, the Max-Air Nose Cone condition PNIF was significantly higher than both the control condition and the nasal strip condition.
Although both the Max-Air Nose Cones and the Breathe Right nasal strips increased PNIF from baseline, the Max-Air Nose Cones showed significantly greater efficacy at stenting the anterior nasal airway, providing twice the improvement in PNIF over baseline than did the Breathe Right nasal strips.
目前有几种设计用于支撑前鼻气道以增加峰值鼻吸气流量 (PNIF) 的鼻腔扩张器;然而,此类设备的比较有限。本研究旨在比较两种不同的鼻腔扩张器的效果,一种是内部设备(Max-Air Nose Cones;Sanostec Corp.,Beverly Farms,MA)和一种外部设备(Breathe Right 鼻贴;GlaxoSmithKline,Brentford,Middlesex,UK)对前鼻气道支架的影响,以最大限度地提高 PNIF。
对 30 名因鼻呼吸不适和鼻气道阻塞而抱怨睡眠呼吸障碍的个体进行 PNIF 的重复测量,同时使用和不使用两种不同的鼻腔扩张器。
对三种情况(对照、Max-Air Nose Cones 和 Breathe Right 鼻贴)进行单因素方差分析(ANOVA),发现具有统计学意义的效果(F[2,58] = 298.13;p<0.00001)。Tukey 事后检验显示,对照条件下的 PNIF(66.07 L/min)明显低于 Max-Air Nose Cones(138.73 L/min)和 Breathe Right 鼻贴(102.17 L/min)条件。Max-Air Nose Cone 增加吸气气流 73 L/min,或比基线提高 110%。此外,Max-Air Nose Cone 条件下的 PNIF 明显高于对照条件和鼻贴条件。
尽管 Max-Air Nose Cones 和 Breathe Right 鼻贴都能使 PNIF 从基线增加,但 Max-Air Nose Cones 在支撑前鼻气道方面的效果明显更好,使 PNIF 比 Breathe Right 鼻贴基线提高了两倍。