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癫痫流行病学的未来方向。

Future directions for epidemiology in epilepsy.

机构信息

National Institute for Intellectual Disability at Trinity College, Dublin, Ireland.

出版信息

Epilepsy Behav. 2011 Sep;22(1):112-7. doi: 10.1016/j.yebeh.2011.06.006. Epub 2011 Aug 4.

Abstract

Epidemiology continues to be an important research tool in the study of epilepsy and related disorders, providing a better understanding of the frequency, causes and natural history of the disorder. But, beyond risk factors and seizure prognosis, epidemiological studies advance knowledge of many other aspects of epilepsy. Epidemiological studies are being conducted in a new environment in which high quality neuroimaging and fast through-put genomic technologies have become routine tools in clinical diagnosis and therapeutics. Epilepsy is currently understood, not as a single, homogeneous disorder, but a multitude of different clinical syndromes and disease, each with its own cause(s), natural history, and treatment implications. That is why; the comorbidites of epilepsy represent an important area, amenable to study, as they may ultimately have a greater impact on quality of life than epilepsy itself. In this document we share our thoughts on what we think are the future directions for epidemiology in epilepsy.

摘要

流行病学仍然是癫痫和相关疾病研究的重要工具,它提供了对该疾病的频率、原因和自然史的更好理解。但是,除了风险因素和癫痫发作预后外,流行病学研究还可以增进对癫痫的许多其他方面的了解。流行病学研究正在新的环境中进行,高质量的神经影像学和快速高通量基因组技术已成为临床诊断和治疗的常规工具。目前,癫痫被理解为不是一种单一的、同质的疾病,而是多种不同的临床综合征和疾病,每种疾病都有其自身的病因、自然史和治疗意义。这就是为什么癫痫的合并症是一个重要的研究领域,因为它们最终可能比癫痫本身对生活质量产生更大的影响。在本文中,我们分享了我们对癫痫流行病学未来发展方向的一些看法。

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