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本文引用的文献

1
Persistence of antibiotic resistance: evaluation of a probiotic approach using antibiotic-sensitive Megasphaera elsdenii strains to prevent colonization of swine by antibiotic-resistant strains.抗生素耐药性的持续存在：使用抗生素敏感型巨球形菌菌株预防猪定植抗生素耐药菌株的益生菌方法评估。
Appl Environ Microbiol. 2011 Oct;77(20):7158-66. doi: 10.1128/AEM.00647-11. Epub 2011 Aug 5.
2
Genetic basis of tetracycline resistance in Bifidobacterium animalis subsp. lactis.双歧杆菌亚种乳亚种中四环素耐药性的遗传基础。
Appl Environ Microbiol. 2010 May;76(10):3364-9. doi: 10.1128/AEM.03096-09. Epub 2010 Mar 26.
3
Tetracycline resistome of the organic pig gut.有机猪肠道的四环素抗性组
Appl Environ Microbiol. 2009 Mar;75(6):1717-22. doi: 10.1128/AEM.02206-08. Epub 2009 Jan 23.
4
ARDB--Antibiotic Resistance Genes Database.ARDB——抗生素抗性基因数据库。
Nucleic Acids Res. 2009 Jan;37(Database issue):D443-7. doi: 10.1093/nar/gkn656. Epub 2008 Oct 2.
5
Detection of Brachyspira hyodysenteriae, Lawsonia intracellularis and Brachyspira pilosicoli in feral pigs.野猪体内猪痢疾短螺旋体、胞内劳森菌和毛发状短螺旋体的检测
Vet Microbiol. 2009 Mar 2;134(3-4):294-9. doi: 10.1016/j.vetmic.2008.08.006. Epub 2008 Aug 22.
6
A new tetracycline efflux gene, tet(40), is located in tandem with tet(O/32/O) in a human gut firmicute bacterium and in metagenomic library clones.一个新的四环素外排基因tet(40)，与tet(O/32/O)串联存在于一种人类肠道厚壁菌以及宏基因组文库克隆中。
Antimicrob Agents Chemother. 2008 Nov;52(11):4001-9. doi: 10.1128/AAC.00308-08. Epub 2008 Sep 8.
7
Mosaic tetracycline resistance genes and their flanking regions in Bifidobacterium thermophilum and Lactobacillus johnsonii.嗜热双歧杆菌和约翰逊乳杆菌中的镶嵌四环素抗性基因及其侧翼区域。
Antimicrob Agents Chemother. 2008 Jan;52(1):248-52. doi: 10.1128/AAC.00714-07. Epub 2007 Oct 29.
8
Influence of antibiotic selection on genetic composition of Escherichia coli populations from conventional and organic dairy farms.抗生素选择对传统和有机奶牛场大肠杆菌菌群遗传组成的影响。
Appl Environ Microbiol. 2007 Oct;73(19):5982-9. doi: 10.1128/AEM.00709-07. Epub 2007 Aug 17.
9
Diagnostic characterization of a feral swine herd enzootically infected with Brucella.对感染布鲁氏菌的野猪群进行诊断特征分析。
J Vet Diagn Invest. 2007 May;19(3):227-37. doi: 10.1177/104063870701900301.
10
Mosaic tetracycline resistance genes are widespread in human and animal fecal samples.镶嵌型四环素抗性基因在人类和动物粪便样本中广泛存在。
Antimicrob Agents Chemother. 2007 Mar;51(3):1115-8. doi: 10.1128/AAC.00725-06. Epub 2006 Dec 18.

有机养殖和野生猪中的金霉素耐药肠道细菌。

Chlortetracycline-resistant intestinal bacteria in organically raised and feral Swine.

机构信息

Food Safety and Enteric Pathogens Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Ames, IA 50010, USA.

出版信息

Appl Environ Microbiol. 2011 Oct;77(20):7167-70. doi: 10.1128/AEM.00688-11. Epub 2011 Aug 5.

DOI:10.1128/AEM.00688-11
PMID:21821750
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3194871/
Abstract

Organically raised swine had high fecal populations of chlortetracycline (CTC)-resistant (growing at 64 μg CTC/ml) Escherichia coli, Megasphaera elsdenii, and anaerobic bacteria. By comparison, CTC-resistant bacteria in feral swine feces were over 1,000-fold fewer and exhibited lower taxonomic diversity.

摘要

有机养殖的猪粪便中含有大量对氯四环素（CTC）具有耐药性的（在 64μg CTC/ml 下生长）大肠杆菌、巨球形菌属和厌氧菌。相比之下，野猪粪便中的 CTC 耐药菌要少 1000 多倍，且具有较低的分类多样性。