Wu Jing, Fushimi Keiji, Tokuyama Shinji, Ohno Masato, Miwa Takaaki, Koyama Tomoyuki, Yazawa Kazunaga, Nagai Kaoru, Matsumoto Tetsuo, Hirai Hirofumi, Kawagishi Hirokazu
Graduate School of Science and Technology, Shizuoka University, Suruga-ku, Shizuoka, Japan.
Biosci Biotechnol Biochem. 2011;75(8):1631-4. doi: 10.1271/bbb.110308. Epub 2011 Aug 7.
Nine compounds (1-9) were isolated from the fruiting bodies of Stropharia rugosoannulata. Compounds 1-5, 8, and 9 suppressed the formation of osteoclast. Compounds 2 and 5 showed anti-fungal activity, and their MIC were 250 µM and 500 µM respectively. Compounds 2-6 showed inhibitory effects on thapsigargin toxicity.
从皱环球盖菇子实体中分离出9种化合物(1-9)。化合物1-5、8和9抑制破骨细胞的形成。化合物2和5表现出抗真菌活性,其最低抑菌浓度分别为250μM和500μM。化合物2-6对毒胡萝卜素毒性有抑制作用。