Stratos Aimilianos A, Peponis Vasileios G, Portaliou Dimitra M, Stroubini Theodora E, Skouriotis Sotirios, Kymionis George D
Ophthalmiatrion Athinon, Athens Eye Hospital, Second Eye Clinic, Athens, Greece.
Optom Vis Sci. 2011 Nov;88(11):1380-2. doi: 10.1097/OPX.0b013e3182297d44.
To report a case of pseudomyopia induced by antipsychotic drug administration.
A 30-year-old woman was referred to our ophthalmology department complaining of blurred vision, especially at distance, in both eyes. The patient had been prescribed antipsychotic drugs (haloperidol and biperiden) as treatment for her schizophrenic symptoms and had recently undergone a change of treatment to amisulpride. She had a manifest refraction of -4.00/-1.00 × 180 in the OD and -3.75/-1.25 × 175 in the OS whereas her cycloplegic refraction was -1.75/-1.00 × 180 in the OD and -1.00/-1.25 × 175 in the OS, respectively.
A diagnosis of likely drug-induced pseudomyopia was made. Therefore, the patient was advised to visit her psychiatrist, who added an extra 2 mg of biperiden, an anticholinergic agent, to the pre-existing amisulpride treatment, achieving a cessation of the visual symptoms a few days later.
Pseudomyopia can be induced by the antipsychotic drug amisulpride. Additional treatment with anticholinergic agents can be used to eliminate this side effect.
报告一例因使用抗精神病药物引起的假性近视病例。
一名30岁女性因双眼视力模糊，尤其是远距离视力模糊，被转诊至我院眼科。该患者因精神分裂症症状接受抗精神病药物（氟哌啶醇和安坦）治疗，近期治疗方案改为氨磺必利。她的右眼明显验光结果为-4.00/-1.00×180，左眼为-3.75/-1.25×175，而其睫状肌麻痹验光结果右眼分别为-1.75/-1.00×180，左眼为-1.00/-1.25×175。
诊断为可能由药物引起的假性近视。因此，建议患者去看精神科医生，医生在现有的氨磺必利治疗方案中额外添加了2毫克安坦（一种抗胆碱能药物），几天后视觉症状消失。
抗精神病药物氨磺必利可引起假性近视。使用抗胆碱能药物进行额外治疗可消除这种副作用。
