Praveen Kumar K V, Chiranjeevi P, Alam Md Shahid
Department of Ophthalmology, Narayana Medical College, Nellore, Andhra Pradesh, India.
Department of Oculoplasty, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Indian J Ophthalmol. 2018 Jan;66(1):130-131. doi: 10.4103/ijo.IJO_907_16.
Aripiprazole is a new drug for the treatment of adults with schizophrenia. Ocular side effects of aripiprazole are very rare. Review of literature revealed few cases of aripiprazole-induced myopia. We report a rare case of aripiprazole-induced transient myopia. A 22-year-old female patient presented to the department of psychiatry with worsening of symptoms of schizophrenia and was started on aripiprazole. She presented with complaints of blurring of vision in both eyes for 1 week which started on the 3rd day following the use of aripiprazole. Anterior segment examination revealed a shallow anterior chamber and narrow angles. Intraocular pressure was normal. A diagnosis of aripiprazole-induced acute myopia was made and the treating psychiatrist was advised to stop the medication. At 2-week follow-up, the unaided visual acuity improved to 20/20 in both the eyes. Ophthalmologists should be aware of the myopic shift that may occur as an ocular side effect with aripiprazole.
阿立哌唑是一种用于治疗成人精神分裂症的新药。阿立哌唑的眼部副作用非常罕见。文献回顾显示，阿立哌唑致近视的病例很少。我们报告一例罕见的阿立哌唑致短暂性近视病例。一名22岁女性患者因精神分裂症症状加重就诊于精神科，并开始服用阿立哌唑。她在使用阿立哌唑后第3天开始出现双眼视力模糊1周的症状。眼前节检查发现前房浅、房角窄。眼压正常。诊断为阿立哌唑致急性近视，并建议主治精神科医生停用该药。在2周的随访中，双眼裸眼视力均提高到20/20。眼科医生应意识到阿立哌唑作为一种眼部副作用可能会导致近视性移位。
