小儿双相情感障碍的治疗：综述
Treatment of Pediatric Bipolar Disorder: A Review.
作者信息
Washburn Jason J, West Amy E, Heil Jennifer A
机构信息
Northwestern University Feinberg School of Medicine, Department of Psychiatry and Behavioral Sciences.
出版信息
Minerva Psichiatr. 2011 Mar;52(1):21-35.
AIM
To review the diagnosis and the pharmacologic and psychosocial interventions for pediatric bipolar disorder (PBD). METHODS: A comprehensive literature review of studies discussing the diagnosis and treatment of PBD was conducted. RESULTS: A context for understanding controversies and difficulties in the diagnosis of PBD is provided. An evidence-based assessment protocol for PBD is reviewed. The evidence for the following three categories of pharmacologic interventions are reviewed: Lithium, antiepileptics, and second generation antipsychotics. Algorithms for medication decisions are briefly reviewed. Existing psychosocial treatments and the evidence for those treatments are also reviewed. CONCLUSION: Despite recent developments in understanding the phenomenology of PBD and in identifying pharmacologic and psychosocial interventions, critical gaps remain.
目的
回顾儿童双相情感障碍（PBD）的诊断以及药物和心理社会干预措施。方法：对讨论PBD诊断和治疗的研究进行全面的文献综述。结果：提供了一个理解PBD诊断中的争议和困难的背景。回顾了基于证据的PBD评估方案。对以下三类药物干预措施的证据进行了综述：锂盐、抗癫痫药和第二代抗精神病药物。简要回顾了药物决策算法。还回顾了现有的心理社会治疗方法及其证据。结论：尽管在理解PBD的现象学以及确定药物和心理社会干预措施方面有了最新进展，但仍存在重大差距。
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