Shi Zhi-Min, Zhu Ye-Shan, Wang Qing-Xian, Lei Miao-Na
Zhongguo Zhen Jiu. 2011 Jul;31(7):607-9.
To compare the differences in the therapeutic effect on irritable bowel syndrome (IBS) between acupuncture at Tianshu (ST 25) and Dachangshu (BL 25) and western medication with Trimebutine Maleate.
Forty cases were divided randomly into an acupuncture group and a western medication group, 20 cases in each one. In acupuncture group, acupuncture was applied to Tianshu (ST 25) and Dachangshu (BL 25). Ziwu Daojiu needling technique was adopted, once daily. In western medication group, Trimebutine Maleate capsule was administered, 2 capsules in each time, 3 times per day. The assessment on the therapeutic effect was performed in 4 weeks of treatment in two groups.
As compared with those before treatment, the time of abdominal pain, the frequency of abdominal pain, the morbidity of abnormal stool appearance, the morbidity of defecation abnormality, the morbidity of mucus stool and the score of bloating or abdominal pain on bowel movement were all reduced after treatment in two groups (all P < 0.01). The results in acupuncture group were much more significant than those in western medication group (the total score: 16.70 +/- 2.40 vs 15.70 +/- 3.01, P < 0.01). The total effective rate in acupuncture group was 95.0% (19/20), which was superior to that of 70.0% (14/20) in western medication group (P < 0.05).
Acupuncture at Tianshu (ST 25) and Dachangshu (BL 25) may remarkably relieve the clinical symptoms of IBS and its efficacy is superior to that of oral medication with Trimebutine Maleate.
比较针刺天枢（ST25）、大肠俞（BL25）与马来酸曲美布汀西药治疗肠易激综合征（IBS）的疗效差异。
将40例患者随机分为针刺组和西药组，每组20例。针刺组针刺天枢（ST25）、大肠俞（BL25），采用子午流注针法，每日1次。西药组口服马来酸曲美布汀胶囊，每次2粒，每日3次。两组均治疗4周后进行疗效评估。
与治疗前比较，两组治疗后腹痛时间、腹痛频率、大便性状异常发生率、排便异常发生率、黏液便发生率及排便时腹胀或腹痛评分均降低（均P<0.01）。针刺组各项结果均较西药组更显著（总分：16.70±2.40 vs 15.70±3.01，P<0.01）。针刺组总有效率为95.0%（19/20），优于西药组的70.0%（14/20）（P<0.05）。
针刺天枢（ST25）、大肠俞（BL25）可显著缓解IBS的临床症状，其疗效优于口服马来酸曲美布汀。
