Li Hao, Pei Li-Xia, Zhou Jun-Ling
The Second Clinical Medical College of Nanjing University of CM, Nanjing 210029, China.
Zhongguo Zhen Jiu. 2012 Aug;32(8):679-82.
To compare the efficacy difference in diarrhea-predominant irritable bowel syndrome between acupuncture in terms of soothing liver and strengthening spleen and western medication.
Seventy cases were randomized into an acupuncture group and a western medication group, 35 cases in each one. In the acupuncture group, the conventional acupuncture was applied to Tianshu (ST 25), Zusanli (ST 36), Shangjuxu (ST 37), Sanyinjiao (SP 6), Taichong (LR 3), etc. The electric stimulation was added at bilateral Tianshu (ST 25). The treatment was given once a day, 3 to 4 treatments required a week. In the western medication group, Pinaverium (Dicetel) was prescribed for oral administration, 50 mg each time, 3 times a day. The treatment of 4 weeks was taken as one session. Separately, before treatment and after one session of treatment, the clinical symptom score and Irritable Bowel Syndrome Quality of Life (IBS-QOL) score were observed for the patients in two groups. The efficacy and the recurrence rate were assessed in two groups.
The symptom score and IBS-QOL score were all improved significantly after treatment in two groups (all P < 0.01). The improvements in the acupuncture group were superior to those in the western medication group (all P < 0.01). The effective rate was 94.3% (33/35) in the acupuncture group, which was better than 77.1% (27/35) in the western medication group (P < 0.01). In 3 months, the recurrence rate was 36.4% (12/33) in the acupuncture group, which was remarkably lower than 72.0% (18/25) in the western medication group (P < 0.01).
Acupuncture in terms of soothing liver and strengthening spleen achieves the superior efficacy on diarrhea-predominant irritable bowel syndrome as compared with western medicine Pinaverium. It remarkably improves the quality of life for the patients and reduces the recurrence rate of the disease.
比较疏肝健脾针法与西药治疗腹泻型肠易激综合征的疗效差异。
将70例患者随机分为针刺组和西药组，每组35例。针刺组采用常规针刺天枢（ST25）、足三里（ST36）、上巨虚（ST37）、三阴交（SP6）、太冲（LR3）等穴位，双侧天枢（ST25）加用电针刺激。每日治疗1次，每周治疗3～4次。西药组口服匹维溴铵（得舒特），每次50mg，每日3次。以4周治疗为1个疗程。分别观察两组患者治疗前及1个疗程治疗后的临床症状评分及肠易激综合征生活质量（IBS-QOL）评分，并评价两组疗效及复发率。
两组治疗后症状评分及IBS-QOL评分均显著改善（均P<0.01），针刺组改善程度优于西药组（均P<0.01）。针刺组有效率为94.3%（33/35），优于西药组的77.1%（27/35）（P<0.01）。3个月内，针刺组复发率为36.4%（12/33），显著低于西药组的72.0%（18/25）（P<0.01）。
疏肝健脾针法治疗腹泻型肠易激综合征疗效优于西药匹维溴铵，能显著提高患者生活质量，降低疾病复发率。
