Yawn B P, Yawn R A, Henning T
Department of Family Medicine and Community Health, University of South Dakota School of Medicine, Sioux Falls.
Fam Med. 1990 Mar-Apr;22(2):122-4.
Group B streptococcus (GBS) is the leading cause of infant mortality from infection. A rapid screening immunoassay for GBS was evaluated in a rural obstetrical population and was found to have an unacceptably low specificity (90%) and sensitivity (50%). With a culture proven GBS colonization rate of 6.8%, the positive predictive value of the rapid screening test was only 27%, and the negative predictive value was 96%. Current recommendations for routine vaginal cultures, on all women based on urban research data with high maternal colonization rates (15%-23%) and high prematurity rates (15%-40%) are reviewed in relation to this community's low colonization and prematurity rates.
B族链球菌（GBS）是婴儿感染性死亡的主要原因。在农村产科人群中对一种GBS快速筛查免疫测定法进行了评估，发现其特异性（90%）和敏感性（50%）低得令人无法接受。经培养证实GBS定植率为6.8%，该快速筛查试验的阳性预测值仅为27%，阴性预测值为96%。结合该社区低定植率和低早产率，对目前基于城市研究数据（高孕产妇定植率为15%-23%，高早产率为15%-40%）对所有妇女进行常规阴道培养的建议进行了审视。
