Schimmel M S, Eidelman A I, Rudensky B, Isacsohn M
Department of Neonatology, Hebrew University-Hadassah Medical School, Shaare Zedek Medical Center, Jerusalem, Israel.
J Perinatol. 1994 May-Jun;14(3):198-200.
Because group B streptococci maternal colonization is a risk factor for the development of neonatal sepsis, a commercially available rapid test was evaluated for its ability to detect intrapartum maternal colonization. A total of 180 paired vaginal swabs were cultured for group B streptococci and assayed by the Equate test. Of the 15 positive cultures, only 1 was detected by the Equate test, resulting in a sensitivity of 7% and a false-negative rate of 93%. The Equate test detected group B streptococci colonization only at a concentration of > or = 10(7) colony-forming units. These results indicate that the Equate test is not adequately sensitive for screening intrapartum populations for group B streptococci colonization.
由于B族链球菌母婴定植是新生儿败血症发生的一个危险因素，因此对一种市售快速检测方法检测产时母亲定植的能力进行了评估。共采集了180对阴道拭子进行B族链球菌培养，并采用Equate检测法进行检测。在15例阳性培养物中，Equate检测法仅检测出1例，灵敏度为7%，假阴性率为93%。Equate检测法仅在浓度≥10⁷ 菌落形成单位时才能检测出B族链球菌定植。这些结果表明，Equate检测法对筛查产时人群的B族链球菌定植不够敏感。
