单次玻璃体内注射贝伐单抗治疗 Sturge-Weber 综合征后浆液性视网膜脱离的快速和持续缓解。
Rapid and sustained resolution of serous retinal detachment in Sturge-Weber syndrome after single injection of intravitreal bevacizumab.
机构信息
Eye Research Center, School of Medicine, Mashhad University Of Medical Sciences, Mashhad, Iran.
出版信息
Ocul Immunol Inflamm. 2011 Oct;19(5):358-60. doi: 10.3109/09273948.2011.589022. Epub 2011 Aug 8.
PURPOSE
To report the effect of a single intravitreal bevacizumab injection on serous retinal detachment (SRD) in Sturge-Weber syndrome (SWS).
DESIGN
Interventional case report.
METHODS
A 15-year-old boy with history of SWS was referred with a complaint of sudden visual loss 2 days before, having choroidal hemangioma accompanied with SRD. Visual acuity was 20/160.
RESULTS
He was treated with 1.25 mg of bevacizumab injected intravitreally. One week later, the retina was completely attached and visual acuity was 20/20. After 20 months, without repeating the injection, the retina remained attached and vision was stable.
CONCLUSIONS
An early single dose of intravitreal bevacizumab is effective in the treatment of serous retinal detachment in SWS with good long-term results.
目的
报告单次玻璃体内注射贝伐单抗治疗脑颜面血管瘤病（SWS）伴浆液性视网膜脱离（SRD）的效果。
设计
介入性病例报告。
方法
一名 15 岁男孩，有 SWS 病史，主诉 2 天前突然视力丧失，伴有脉络膜血管瘤伴 SRD。视力为 20/160。
结果
给予 1.25mg 贝伐单抗玻璃体内注射。1 周后，视网膜完全贴附，视力为 20/20。20 个月后，无需重复注射，视网膜仍保持贴附，视力稳定。
结论
早期单次玻璃体内注射贝伐单抗治疗 SWS 伴浆液性视网膜脱离有效，长期效果良好。
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