Department of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, Ontario L8N 1Y2, Canada.
Alcohol. 2012 Mar;46(2):165-72. doi: 10.1016/j.alcohol.2011.07.001. Epub 2011 Aug 6.
This study compared differences in risk for suicidality among youth living in the community who met criteria for comorbid depression and binge drinking, depression without binge drinking, and binge drinking without depression relative to a reference group with neither condition. Logistic regression analysis was used to analyze data from the Canadian Community Health Survey, Cycle 3.1 (CCHS 3.1, 2005): a cross-sectional survey of respondents from the Canadian population. To restrict the sample to youth, respondents were excluded who were younger than 15 or older than 24 years. Over 17,000 respondents were assessed to determine whether they met criteria for depression, binge drinking, the comorbid condition, or neither condition (reference group). Binge drinking was defined as five drinks or more on an occasion. The 12-month prevalence rates for comorbid binge drinking and depression were 2.7% for male respondents and 2.1% for female respondents. When adjusted for demographic factors and when compared with the reference group, the risk of suicidality was increased for the depressed group (odds ratio [OR] 5.23, 95% confidence interval [CI]: 3.34-8.2) and the comorbid group (OR 6.28, 95% CI: 3.68-10.70), but not for the binge-drinking group. With the exception of increasing age, sociodemographic factors were not correlates of comorbidity. In conclusion, binge drinking was not associated with an increased risk of suicidality among Canadian youth living in the community, although depression and comorbidity were associated with suicidality.
本研究比较了符合共病抑郁和 binge drinking、抑郁但无 binge drinking、binge drinking 但无抑郁的社区青少年与既无共病又无 binge drinking 的参考组相比,自杀风险的差异。采用逻辑回归分析方法分析了加拿大社区健康调查,第 3.1 期(CCHS 3.1,2005 年)的数据:这是对加拿大人口中调查对象的横断面调查。为了将样本限制为青少年,排除了年龄小于 15 岁或大于 24 岁的调查对象。对超过 17000 名调查对象进行评估,以确定他们是否符合抑郁、binge drinking、共病或既无共病又无 binge drinking 的标准(参考组)。binge drinking 定义为一次饮酒 5 杯或以上。男性调查对象的 12 个月共病 binge drinking 和抑郁的患病率为 2.7%,女性为 2.1%。调整人口统计学因素后,与参考组相比,抑郁组的自杀风险增加(比值比 [OR] 5.23,95%置信区间 [CI]:3.34-8.2)和共病组(OR 6.28,95% CI:3.68-10.70),但 binge drinking 组则不然。除了年龄增长,社会人口统计学因素与共病无关。总之,在加拿大社区生活的青少年中,binge drinking 与自杀风险增加无关,尽管抑郁和共病与自杀风险相关。