Nuffield Orthopaedic Centre, Windmill Road Headington, Oxford OX3 7LD, UK.
Int Orthop. 2012 Apr;36(4):731-4. doi: 10.1007/s00264-011-1332-5. Epub 2011 Aug 9.
Although originally designed for reconstruction after primary malignant bone tumour resection, modular endoprosthetic replacement (EPR) can be used in salvage surgery for complex periprosthetic fracture and failed internal fixation. The purpose of this study was to assess the functional outcome following EPR for failed internal fixation of the proximal femur.
We assessed clinical and functional outcomes of using a modular tumour endoprosthesis to reconstruct the proximal femur following failed internal fixation in eight consecutive patients between 2001 and 2008.
There were four men and four women, with a mean age of 67.5 (range 50-79) years and a mean follow-up of 16.5 (6-36) months. All patients had failed internal fixation for traumatic proximal femoral fractures--four 31.A2.3, two 31.A3.1, two 31.A3.3 using the Arbeitsgemeinshaft für Osteosynthesefragen (AO) fracture classification. Mean time from the first attempted internal fixation to definitive EPR was 34 (6-102) months, and the median number of previous surgical procedures was two (1-11). Histology revealed infection (two cases), uninfected nonunion (five cases) and plasmocytoma (one case). The EPR was carried out as a one-stage procedure in six cases and a two-stage procedure in two cases. Mean postoperative Harris Hip Score was 71.4 (range 64-85). There were no surgical complications. One patient died as a result of systemic complications of myeloma several years following EPR.
EPR is an effective salvage procedure for failed fixation of traumatic proximal femoral fractures. Immediate weightbearing and a good functional outcome can be expected in this difficult group of patients.
尽管最初设计用于原发性恶性骨肿瘤切除后的重建,但模块化内置假体置换(EPR)可用于复杂的假体周围骨折和内固定失败的挽救性手术。本研究的目的是评估 EPR 治疗股骨近端内固定失败后的功能结果。
我们评估了 2001 年至 2008 年间连续 8 例使用模块化肿瘤假体重建股骨近端内固定失败的患者的临床和功能结果。
4 例男性,4 例女性,平均年龄 67.5 岁(50-79 岁),平均随访 16.5 个月(6-36 个月)。所有患者均因创伤性股骨近端骨折而发生内固定失败,4 例为 31.A2.3,2 例为 31.A3.1,2 例为 31.A3.3,采用 Arbeitsgemeinshaft für Osteosynthesefragen(AO)骨折分类。从首次尝试内固定到最终 EPR 的平均时间为 34 个月(6-102 个月),中位数为 2 次(1-11 次)。组织学显示感染(2 例)、无感染性骨不连(5 例)和浆细胞瘤(1 例)。6 例患者行一期手术,2 例患者行二期手术。术后平均 Harris 髋关节评分 71.4 分(64-85 分)。无手术并发症。1 例患者在 EPR 后几年因骨髓瘤全身并发症死亡。
EPR 是治疗创伤性股骨近端骨折内固定失败的有效挽救性手术。在这组困难的患者中,可以预期立即负重和良好的功能结果。