Section of Environmental Health, University of Copenhagen, Copenhagen, Denmark.
PLoS One. 2011;6(7):e22904. doi: 10.1371/journal.pone.0022904. Epub 2011 Jul 29.
One of the key climate change factors, temperature, has potentially grave implications for human health. We report the first attempt to investigate the association between the daily 3-hour maximum apparent temperature (Tapp(max)) and respiratory (RD), cardiovascular (CVD), and cerebrovascular (CBD) emergency hospital admissions in Copenhagen, controlling for air pollution. The study period covered 1 January 2002-31 December 2006, stratified in warm and cold periods. A case-crossover design was applied. Susceptibility (effect modification) by age, sex, and socio-economic status was investigated. For an IQR (8°C) increase in the 5-day cumulative average of Tapp(max), a 7% (95% CI: 1%, 13%) increase in the RD admission rate was observed in the warm period whereas an inverse association was found with CVD (-8%, 95% CI: -13%, -4%), and none with CBD. There was no association between the 5-day cumulative average of Tapp(max) during the cold period and any of the cause-specific admissions, except in some susceptible groups: a negative association for RD in the oldest age group and a positive association for CVD in men and the second highest SES group. In conclusion, an increase in Tapp(max) is associated with a slight increase in RD and decrease in CVD admissions during the warmer months.
一个关键的气候变化因素,温度,对人类健康可能产生严重影响。我们首次尝试调查在哥本哈根,控制空气污染的情况下,每日 3 小时最高明显温度(Tapp(max))与呼吸(RD)、心血管(CVD)和脑血管(CBD)急诊入院之间的关联。研究期间为 2002 年 1 月 1 日至 2006 年 12 月 31 日,分为温暖期和寒冷期。应用病例交叉设计。研究了年龄、性别和社会经济地位的易感性(效应修饰)。在温暖期,Tapp(max)的 5 天累积平均值每增加一个 IQR(8°C),RD 入院率增加 7%(95%CI:1%,13%),而 CVD 则呈反比关系(-8%,95%CI:-13%,-4%),与 CBD 无关。在寒冷期,Tapp(max)的 5 天累积平均值与任何特定原因的入院率均无关联,除了一些易感人群:RD 在最年长的年龄组中呈负相关,CVD 在男性和第二高 SES 组中呈正相关。总之,Tapp(max)的增加与温暖月份 RD 入院率略有增加和 CVD 入院率略有下降有关。