Suppr超能文献

未用药、自主的酒精戒断评估。

Evaluation of un-medicated, self-paced alcohol withdrawal.

机构信息

Nottingham Substance Misuse Service, Nottingham, United Kingdom.

出版信息

PLoS One. 2011;6(7):e22994. doi: 10.1371/journal.pone.0022994. Epub 2011 Jul 28.

Abstract

It is currently unclear how effective un-medicated, self-paced alcohol withdrawal is in reducing alcohol consumption in alcohol dependent clients. To address this question, the current study examined the reduction in alcohol consumption, assessed by breath alcohol and drink diary self-report, of 405 alcohol-dependent clients over a 10-day, un-medicated, self-paced alcohol reduction program that included group discussion of strategies for titrating between withdrawal and intoxication. It was found that attendance at treatment sessions was associated with a reduction in alcohol consumption, reflected in both breath alcohol and diary measures, and these two measures were significantly correlated. Overall, 35% of clients achieved a zero breath alcohol reading by their final session, although this percentage increased to 56% of clients who attended all 10 sessions. Withdrawal seizures occurred in only 0.5% of clients despite 17.2% having a history of seizures in other settings. It is concluded that the alcohol reduction protocol outlined here provides an effective and safe method for reducing alcohol consumption in severely alcohol dependent clients, and that methods for augmenting attendance, such as contingency management, should enhance the effectiveness of this treatment.

摘要

目前尚不清楚无药物、自我 paced 的酒精戒断在减少酒精依赖患者的饮酒量方面的效果如何。为了解决这个问题,本研究在 10 天内,通过呼吸酒精和饮酒日记自我报告,对 405 名酒精依赖患者进行了评估,研究了无药物、自我 paced 的酒精减少计划对减少饮酒量的效果,该计划包括讨论在戒断和醉酒之间调整的策略。结果发现,参加治疗课程与饮酒量减少有关,这反映在呼吸酒精和日记测量两个方面,并且这两个测量值显著相关。总体而言,35%的患者在最后一次治疗时达到了零呼吸酒精读数,尽管参加了全部 10 次治疗的患者的这一比例增加到了 56%。尽管有 17.2%的患者在其他环境中有癫痫发作史,但只有 0.5%的患者出现戒断性癫痫发作。研究结论是,这里概述的酒精减少方案为严重酒精依赖患者减少饮酒量提供了一种有效且安全的方法,并且增加出勤率的方法,例如,通过强化管理,应该可以提高这种治疗的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3aab/3145777/97f811ab25ec/pone.0022994.g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验