United States Naval Medical Research Unit 6, Lima, Peru.
PLoS One. 2011;6(8):e22111. doi: 10.1371/journal.pone.0022111. Epub 2011 Aug 1.
Human respiratory syncytial virus (HRSV) is a major cause of viral lower respiratory tract infections among infants and young children. HRSV strains vary genetically and antigenically and have been classified into two broad subgroups, A and B (HRSV-A and HRSV-B, respectively). To date, little is known about the circulating strains of HRSV in Latin America. We have evaluated the genetic diversity of 96 HRSV strains by sequencing a variable region of the G protein gene of isolates collected from 2007 to 2009 in Central and South America. Our results show the presence of the two antigenic subgroups of HRSV during this period with the majority belonging to the genotype HRSV-A2.
人呼吸道合胞病毒（HRSV）是导致婴幼儿下呼吸道感染的主要病原体。HRSV 株在基因和抗原上存在差异，可分为两个主要亚群，A 和 B（分别为 HRSV-A 和 HRSV-B）。迄今为止，人们对拉丁美洲流行的 HRSV 株知之甚少。我们通过对 2007 年至 2009 年期间在中美洲和南美洲采集的分离株 G 蛋白基因的可变区进行测序，评估了 96 株 HRSV 株的遗传多样性。研究结果表明，在此期间存在两种 HRSV 抗原亚群，其中大多数属于 HRSV-A2 基因型。
