Vranesić-Bender Darija
Center of Clinical Nutrition, Zagreb University Hospital Center, Zagreb, Croatia.
Acta Clin Croat. 2010 Dec;49(4):537-44.
'Nutraceuticals' is a wide term including all kinds of food with health or medical effect. Regulations in the world on functional food and nutraceuticals are developed along with the development of new products. This nomenclature is not aligned across legal regulations in different countries. There are several theories trying to interpret the phenomenon of aging and the most interesting theory in terms of nutrition is free radical theory and the possible role of antioxidants in aging process. A large group of substances including vitamins, carotenoids, flavonoids and minerals have in vitro or in vivo clinically significant antioxidant characteristics. There is great interest in anti-aging substances derived from food, and the most popular ingredients are antioxidants, especially coenzyme Q10, phytoestrogens, probiotics and omega-3 fatty acids. These substances have beneficial effect on digestive and immune systems, and modulate inflammatory and degenerative processes in the body. The challenge in the future will be strategic combining of cosmeceuticals and nutraceuticals in order to intervene in biological aging processes and degenerative skin changes.
“营养保健品”是一个宽泛的术语，包括各类具有健康或医疗功效的食品。世界上关于功能性食品和营养保健品的法规是随着新产品的发展而制定的。不同国家的法律法规对这一术语的界定并不一致。有几种理论试图解释衰老现象，从营养角度来看，最有趣的理论是自由基理论以及抗氧化剂在衰老过程中可能发挥的作用。一大类物质，包括维生素、类胡萝卜素、黄酮类化合物和矿物质，在体外或体内都具有临床上显著的抗氧化特性。人们对源自食物的抗衰老物质兴趣浓厚，最受欢迎的成分是抗氧化剂，尤其是辅酶Q10、植物雌激素、益生菌和ω-3脂肪酸。这些物质对消化系统和免疫系统有有益作用，并调节体内的炎症和退行性过程。未来的挑战将是战略性地将药妆品和营养保健品结合起来，以干预生物衰老过程和皮肤退行性变化。
