多位点可变数目串联重复分析与多位点序列分型在溶血性尿毒综合征相关大肠埃希菌（HUSEC）分离株鉴定中的比较。
Comparison of multilocus variable-number tandem-repeat analysis and multilocus sequence typing for differentiation of hemolytic-uremic syndrome-associated Escherichia coli (HUSEC) collection strains.
机构信息
Institute of Hygiene and National Consulting Laboratory for Hemolytic Uremic Syndrome, University Hospital Münster, Robert-Koch-Strasse 41, 48149 Münster, Germany.
出版信息
J Clin Microbiol. 2011 Oct;49(10):3644-6. doi: 10.1128/JCM.05035-11. Epub 2011 Aug 10.
Abstract
Multilocus variable-number tandem-repeat analysis (MLVA) was compared to multilocus sequence typing (MLST) to differentiate hemolytic uremic syndrome-associated enterohemorrhagic Escherichia coli strains. Although MLVA--like MLST--was highly discriminatory (index of diversity, 0.988 versus 0.984), a low level of concordance demonstrated the limited ability of MLVA to reflect long-term evolutionary events.
摘要
多位点可变数目串联重复分析（MLVA）与多位点序列分型（MLST）相比较，用于区分溶血性尿毒症综合征相关肠出血性大肠杆菌菌株。虽然 MLVA 与 MLST 一样具有高度的区分度（多样性指数分别为 0.988 和 0.984），但其一致性水平较低表明 MLVA 反映长期进化事件的能力有限。
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