溶血尿毒综合征相关肠出血性大肠杆菌的菌株分析
Analysis of collection of hemolytic uremic syndrome-associated enterohemorrhagic Escherichia coli.
作者信息
Mellmann Alexander, Bielaszewska Martina, Köck Robin, Friedrich Alexander W, Fruth Angelika, Middendorf Barbara, Harmsen Dag, Schmidt M Alexander, Karch Helge
机构信息
Institute for Hygiene and the National Consulting Laboratory on Hemolytic Uremic Syndrome, Münster, Germany.
出版信息
Emerg Infect Dis. 2008 Aug;14(8):1287-90. doi: 10.3201/eid1408.071082.
Abstract
Multilocus sequence typing of 169 non-O157 enterohemorrhagic Escherichia coli (EHEC) isolated from patients with hemolytic uremic syndrome (HUS) demonstrated 29 different sequence types (STs); 78.1% of these strains clustered in 5 STs. From all STs and serotypes identified, we established a reference panel of EHEC associated with HUS (HUSEC collection).
摘要
对从溶血尿毒综合征（HUS）患者中分离出的169株非O157肠出血性大肠杆菌（EHEC）进行多位点序列分型，结果显示有29种不同的序列类型（STs）；其中78.1%的菌株聚集在5种STs中。从所有鉴定出的STs和血清型中，我们建立了一个与HUS相关的EHEC参考菌株库（HUSEC菌株库）。
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2
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3
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Sex and virulence in Escherichia coli: an evolutionary perspective.大肠杆菌中的性别与毒力：进化视角
Mol Microbiol. 2006 Jun;60(5):1136-51. doi: 10.1111/j.1365-2958.2006.05172.x.
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8
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