Peyyala R, Kirakodu S, Novak K F, Ebersole J L
Center for Oral Health Research, College of Dentistry, University of Kentucky, 414 HSRB, 1095 VA Drive, Lexington, KY 40536, USA.
Clin Vaccine Immunol. 2011 Oct;18(10):1770-2. doi: 10.1128/CVI.05162-11. Epub 2011 Aug 10.
An in vitro model of bacterial biofilms on rigid gas-permeable contact lenses (RGPLs) was developed to challenge oral epithelial cells. This novel model provided seminal data on oral biofilm-host cell interactions, and with selected bacteria, the biofilms were more effective than their planktonic counterparts at stimulating host cell responses.
开发了一种用于硬质透气隐形眼镜(RGPLs)上细菌生物膜的体外模型,以挑战口腔上皮细胞。这个新模型提供了关于口腔生物膜与宿主细胞相互作用的重要数据,并且对于选定的细菌,生物膜在刺激宿主细胞反应方面比其浮游形式更有效。