Otoshi Taiyo, Kobayashi Ken-Ichi, Madono Keigo, Momohara Chikahiro, Imamura Ryoichi, Takada Shingo, Yamasaki Takashi, Tsujimoto Masahiko, Matsumiya Kiyomi
The Department of Urology, Osaka Police Hospital.
Hinyokika Kiyo. 2011 Jul;57(7):377-80.
A 63-year-old woman with a right renal tumor diagnosed by ultrasound, consulted our hospital in October 2008. The findings of her physical examination were unremarkable. The results of urinalysis and other routine blood tests were normal. The urinary cytology was negative for malignant cells. Dynamic computed tomography showed a right renal mass (diameter, 7.5 cm), which was enhanced in the early phase and washed out in the late phase. We initially thought that the patient had renal cell carcinoma. Therefore, laparoscopic right nephrectomy was performed in October 2008. The tumor section was found to be encapsulated, and focal hemorrhage and necrosis were observed. Histological examination of the tumor by hematoxylin-eosin staining revealed that it contained polygonal cells, eosinophilic cytoplasm and large nuclei. Immunohistochemical staining of anticytokeratin antibodies AE1/AE3 and CAM5.2 (markers for renal cell carcinoma) was negative. However, immunohistochemical staining of HMB-45, a marker for melanoma, was positive. The patient was finally diagnosed with epithelioid angiomyolipoma. She did not show any evidence of tumor recurrence for 25 months after the surgery.
一名63岁女性因超声检查发现右肾肿瘤，于2008年10月前来我院就诊。其体格检查结果无异常。尿液分析及其他常规血液检查结果均正常。尿细胞学检查未发现恶性细胞。动态计算机断层扫描显示右肾有一肿块（直径7.5厘米），早期强化，晚期廓清。我们最初认为该患者患有肾细胞癌。因此，于2008年10月进行了腹腔镜右肾切除术。发现肿瘤切面有包膜，可见局灶性出血和坏死。苏木精-伊红染色的肿瘤组织学检查显示，肿瘤含有多边形细胞、嗜酸性细胞质和大细胞核。抗细胞角蛋白抗体AE1/AE3和CAM5.2（肾细胞癌标志物）的免疫组化染色为阴性。然而，黑色素瘤标志物HMB-45的免疫组化染色为阳性。该患者最终被诊断为上皮样血管平滑肌脂肪瘤。术后25个月未出现任何肿瘤复发迹象。
