Wada Akinori, Maezawa Takuya, Kageyama Susumu, Johnin Kazuyoshi, Narita Mitsuhiro, Okada Yusaku
The Department of Urology, Shiga University of Medical Science.
Hinyokika Kiyo. 2011 Jul;57(7):381-3.
A 65-year-old man presented with gross hematuria in 2004. Computed tomography (CT) showed a left renal mass, and he underwent laparoscopic radical nephrectomy. Pathological diagnosis was clear cell carcinoma (pT2N0M0, G2＞G3). Four years later, a right adrenal tumor was disclosed by follow-up CT. Then laparoscopic adrenectomy was performed. Histology showed metastasis of the renal clear cell carcinoma. In 2009, he noticed gross hematuria, and cystoscopy revealed a 2cm solitary, non-papillary tumor at the anterior wall of the bladder. At the same time, small solitary liver metastasis (6 mm) was observed on abdominal CT. Transurethral resection of the bladder tumor and resection of liver tumor was performed, and pathological diagnosis was clear cell carcinoma both in vesical and hepatic masses. Nine months after the last surgery, he is living with no obvious tumor recurrence. To our knowledge this case is the 34th case of bladder metastasis from renal cell carcinoma in the Japanese literature. We reviewed literature and discuss the clinical features of bladder metastasis of renal cell carcinoma.
一名65岁男性于2004年出现肉眼血尿。计算机断层扫描（CT）显示左肾肿块，随后他接受了腹腔镜根治性肾切除术。病理诊断为透明细胞癌（pT2N0M0，G2＞G3）。四年后，随访CT发现右肾上腺肿瘤，遂行腹腔镜肾上腺切除术。组织学检查显示为肾透明细胞癌转移。2009年，他再次出现肉眼血尿，膀胱镜检查发现膀胱前壁有一个2cm的孤立性、非乳头状肿瘤。同时，腹部CT观察到肝脏有一个6mm的小孤立性转移灶。遂行膀胱肿瘤经尿道切除术及肝肿瘤切除术，病理诊断膀胱和肝脏肿块均为透明细胞癌。最后一次手术后九个月，他目前生活状态良好，无明显肿瘤复发迹象。据我们所知，该病例是日本文献中第34例肾细胞癌膀胱转移病例。我们回顾了相关文献并讨论了肾细胞癌膀胱转移的临床特征。
