Nitta Satoshi, Suetomi Takahiro, Kojou Kousuke, Tanaka Ken, Kurobe Masahiro, Yoshino Takayuki, Yamazaki Kazumitu, Kimura Tomokazu, Kandori Shuya, Kawahara Takashi, Kawai Kouji, Miyazaki Jun, Yano Youko, Yamada Kenji, Noguchi Masayuki, Nishiyama Hiroyuki
The Department of Urology, Jikei University School of Medicine.
The Department of Urology, Tsukuba Gakuen Hospital.
Hinyokika Kiyo. 2016 Feb;62(2):63-7.
Bladder metastasis of renal cell carcinoma (RCC) is relatively rare, and only 43 cases have been reported in the Japanese literature. In most cases, the histology of the primary site was clear cell type. Here, we report a case of bladder metastasis of chromophobe RCC. A 74-year-old man presented with asymptomatic gross hematuria. He had a history of chromophobe RCC treated with radical nephrectomy 11 years previously. Since cystoscopy revealed a papillary pedunculated tumor, he underwent transurethral resection of the bladder tumor (TUR-Bt). The pathological diagnosis was chromophobe RCC because the histological findings were similar to those of nephrectomized specimens. Four years after TUR-Bt, the patient received bacillus Calmette-Guérin (BCG) therapy under the diagnosis of carcinoma in situ of urothelial cancer of the bladder but not chromophobe RCC. There was no recurrence of chromophobe RCC within 5 years follow-up after TUR-Bt. To the best of our knowledge, there has been only one other case report of bladder metastasis of chromophobe RCC in the Japanese literature.
肾细胞癌（RCC）的膀胱转移相对罕见，日本文献中仅报道过43例。大多数情况下，原发部位的组织学类型为透明细胞型。在此，我们报告一例嫌色性RCC膀胱转移病例。一名74岁男性因无症状肉眼血尿就诊。他11年前曾因嫌色性RCC接受根治性肾切除术。由于膀胱镜检查发现一个带蒂乳头状肿瘤，他接受了经尿道膀胱肿瘤切除术（TUR-Bt）。病理诊断为嫌色性RCC，因为组织学表现与肾切除标本相似。TUR-Bt术后4年，患者在膀胱尿路上皮癌原位癌而非嫌色性RCC的诊断下接受了卡介苗（BCG）治疗。TUR-Bt术后5年随访期间，嫌色性RCC无复发。据我们所知，日本文献中仅有另一例嫌色性RCC膀胱转移的病例报告。
