Department of Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia Vancouver, BC, Canada.
Front Pharmacol. 2010 Nov 16;1:136. doi: 10.3389/fphar.2010.00136. eCollection 2010.
Diabetic cystopathy is a well-recognized complication of diabetes mellitus, which usually develops in middle-aged or elderly patients with long-standing and poorly controlled disease. It may have broad spectrum clinical presentations. Patients may be asymptomatic, or have a wide variety of voiding complaints from overactive bladder and urge incontinence to decreased bladder sensation and overflow incontinence. This review focuses on pathophysiological mechanisms responsible for urologic complications of diabetes and emphasizing on recent developments in our understanding of this condition. We also tried to shed some light on therapeutic modalities like behavioral, pharmacological, and surgical approaches.
糖尿病性膀胱病是糖尿病的一种公认并发症，通常发生于中年或老年患者，且具有长期未得到控制的病史。它可能具有广泛的临床表现。患者可能无症状，也可能有各种各样的排尿问题，从膀胱过度活动和急迫性尿失禁到膀胱感觉减退和充盈性尿失禁。本文重点讨论了导致糖尿病泌尿系统并发症的病理生理机制，并强调了我们对该病认识的最新进展。我们还尝试探讨了治疗方法，如行为、药物和手术方法。
