V.K. Chavan-Patil Arts, Commerce and Science Senior College, Shivaji University, Chandgad, India.
Drug Chem Toxicol. 2012 Apr;35(2):178-83. doi: 10.3109/01480545.2011.589608. Epub 2011 Aug 11.
The toxicity of sodium cyanide to the freshwater fish, Tilapia mossambica, was studied using the static bioassay method. The LC(50) value at 96 hours was found to be 44.33 µg/L (normal concentration is 25 µg/L). Behavioral changes, when exposed to a lethal concentration of sodium cyanide, showed increased opercular movement, increased surface behavior, loss of equilibrium, change in body color, increased secretion of mucus, irregular swimming activity, rapid jerk movement, "S" jerk, partial jerk, and aggressiveness. A decrease in ammonia level of gill (67.56%), muscle (63.88%), and liver (53.29%) with increased levels in urea gill (75.83%), muscle (63.53%), and liver (107.49%) was observed in a lethal concentration of sodium cyanide at the end of day 4 of exposure. In a sublethal concentration (4.43 μg/L), a decreasing trend in ammonia level continued up to day 15. Urea level at days 1 and 5 decreased on days 1 and 5, but increased on days 10 and 15.
采用静态生物测定法研究了氰化钠对淡水鱼罗非鱼的毒性。96 小时时的 LC50 值为 44.33µg/L（正常浓度为 25µg/L）。在暴露于致死浓度的氰化钠时，出现了行为变化，包括鳃盖运动增加、表面行为增加、失去平衡、体色变化、黏液分泌增加、游泳活动不规则、快速抽搐、“S”型抽搐、部分抽搐和攻击性。在第 4 天暴露于致死浓度的氰化钠时，观察到鳃（67.56%）、肌肉（63.88%）和肝脏（53.29%）中氨水平下降，而鳃（75.83%）、肌肉（63.53%）和肝脏（107.49%）中尿素水平升高。在亚致死浓度（4.43µg/L）下，氨水平的下降趋势持续到第 15 天。第 1 天和第 5 天的尿素水平在第 1 天和第 5 天下降，但在第 10 天和第 15 天上升。
