Berger U, Khaghani A, Pomerance A, Yacoub M H, Coombes R C
Clinical Oncology Department, St. George's Hospital Medical School, London, United Kingdom.
Am J Clin Pathol. 1990 May;93(5):609-14. doi: 10.1093/ajcp/93.5.609.
Estrogen and progesterone receptors were demonstrated immunocytochemically in the lung tissue of two cases of pulmonary lymphangioleiomyomatosis. In one case both receptors were localized in the proliferative smooth muscle nodules and diffusely in the interstitial tissue in close proximity to the muscle. The pulmonary tissue in the other case contained the estrogen receptor only. The authors conclude that the response to hormonal treatment seen in this disease might be optimized in the future by monitoring for the presence of steroid hormone receptors.
通过免疫细胞化学方法在两例肺淋巴管平滑肌瘤病患者的肺组织中检测到雌激素和孕激素受体。在其中一例中，两种受体均定位于增生性平滑肌结节中，并在紧邻肌肉的间质组织中呈弥漫性分布。另一例患者的肺组织中仅含有雌激素受体。作者得出结论，未来通过监测类固醇激素受体的存在，可能会优化该疾病中激素治疗的效果。
