Rozhanets V V, Promyslov M Sh, Gabriélian N I, Shcherbaneva O I
Vopr Med Khim. 1979 Jan-Feb;25(1):71-4.
Liquor cerebrospinalis, obtained from patients with various diseases, inhibited Na, K-ATPase from rat and bovine synaptic membranes and did not influence on the activity of Mg-ATPase. The inhibition was independent on the type of disease. The inhibitory effect of liquor cerebrospinalis disappeared after dyalisis of it against Krebs-Ringer solution. Liquor cerebrospinalis appears to contain an endogenous inhibitor of synaptic Na,K-ATPase, which controls the enzymatic activity in vivo.
从患有各种疾病的患者身上获取的脑脊液，可抑制大鼠和牛突触膜中的钠钾ATP酶，而对镁ATP酶的活性没有影响。这种抑制作用与疾病类型无关。脑脊液经 Krebs-Ringer 溶液透析后，其抑制作用消失。脑脊液似乎含有一种内源性突触钠钾ATP酶抑制剂，该抑制剂在体内控制着酶的活性。
