Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Curr Opin Obstet Gynecol. 2011 Oct;23(5):366-70. doi: 10.1097/GCO.0b013e32834a926e.
To review the predictors for overactive bladder (OAB) symptoms after pelvic organ prolapse (POP) surgery.
In general, an improvement on OAB can be expected after POP surgery. There are few studies which study the predictors of OAB after POP surgery and most studies had a different perspective. Some studies made conclusions on the basis of multivariate analysis, in which all relevant factors were taken into account. On the basis of these studies, it seems that various factors influence the results on OAB symptoms after POP surgery. Predictors for improvement gave a confusing and sometimes contradicting results. The role of preoperative detrusor overactivity is unclear, improvement as well as persistence of OAB was found. Further, the detrusor opening pressure and maximum flow rate seem to play a role. The absence of bothersome OAB preoperatively was a further predictor for absence of postoperative symptoms. Further, it was found that the individual OAB symptoms had different predictors. All together, the results of the various studies are inconclusive. It is therefore at present essentially still impossible to reliably predict the presence of OAB after POP surgery.
More research is necessary on the predictors for OAB after POP surgery.
综述目的：综述盆腔器官脱垂（POP）手术后膀胱过度活动症（OAB）症状的预测因素。
最新发现：一般来说，POP 手术后 OAB 症状会有所改善。研究 OAB 预测因素的研究较少，且大多数研究的观点不同。一些研究在多变量分析的基础上得出了结论，其中考虑了所有相关因素。基于这些研究，似乎有多种因素影响 POP 手术后 OAB 症状的结果。改善的预测因素给出了令人困惑且有时相互矛盾的结果。术前逼尿肌过度活动的作用尚不清楚，OAB 既可以改善也可以持续存在。此外，膀胱开口压和最大流量似乎也起作用。术前无明显 OAB 症状是术后无症状的另一个预测因素。此外，还发现个体 OAB 症状有不同的预测因素。总之，各项研究的结果尚无定论。因此，目前基本上仍然不可能可靠地预测 POP 手术后 OAB 的存在。
总结：需要对 POP 手术后 OAB 的预测因素进行更多的研究。
