Diez-Itza I, Aizpitarte I, Becerro A, Sarasqueta C
Department of Obstetrics and Gynaecology, Hospital Donostia, San Sebastián, Spain.
Gynecol Obstet Invest. 2009;68(1):65-70. doi: 10.1159/000215711. Epub 2009 Apr 30.
The aim of this study was to determine the incidence of overactive bladder (OAB) after vaginal hysterectomy for pelvic organ prolapse (POP) and analyze the associated risk factors.
This was a retrospective cohort study of 217 patients who underwent primary POP vaginal surgery between the years 2000 and 2004 in Donostia Hospital and who did not report OAB before surgery. A personal interview was undertaken after surgery for the diagnosis of OAB, taking into account the ICS 2002 definition. Descriptive statistical analyses and multivariate logistic regression were performed to determine the factors associated with the development of OAB after POP surgery.
De novo OAB was diagnosed in 43 (19.8%) patients. The median time at onset of OAB symptoms after surgery was 3 months. Urge urinary incontinence was present in 28 patients (12.9%). Those women operated on also for stress urinary incontinence were at an increased risk for de novo OAB.
Nearly 20% of women operated on for POP develop OAB soon after surgery. Those operated on for POP and stress urinary incontinence are more at risk.
本研究旨在确定盆腔器官脱垂（POP）行阴道子宫切除术后膀胱过度活动症（OAB）的发生率，并分析相关危险因素。
这是一项回顾性队列研究，研究对象为2000年至2004年期间在多诺斯蒂亚医院接受初次POP阴道手术且术前未报告有OAB的217例患者。术后进行个人访谈以诊断OAB，诊断时考虑国际尿控学会（ICS）2002年的定义。进行描述性统计分析和多因素逻辑回归分析，以确定POP手术后与OAB发生相关的因素。
43例（19.8%）患者诊断为新发OAB。术后OAB症状出现的中位时间为3个月。28例患者（12.9%）存在急迫性尿失禁。那些同时接受压力性尿失禁手术的女性发生新发OAB的风险增加。
近20%接受POP手术的女性术后不久会发生OAB。接受POP和压力性尿失禁手术的女性风险更高。
