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2-(4-氟苯基)-3-甲基-1H-吲哚

2-(4-Fluoro-phen-yl)-3-methyl-1H-indole.

作者信息

Cordes David B, Hua Guoxiong, Slawin Alexandra M Z, Woollins J Derek

机构信息

School of Chemistry, University of St Andrews, Fife KY16 9ST, Scotland.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Jul 1;67(Pt 7):o1606. doi: 10.1107/S1600536811021325. Epub 2011 Jun 11.

DOI:10.1107/S1600536811021325
PMID:21837014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3151858/
Abstract

The indole N-H hydrogen in the title compound, C(15)H(12)FN, does not display classical hydrogen bonding. Rather it forms an interaction with the π system of an adjacent indole, resulting in weakly inter-acting chains along the [001] direction.

摘要

标题化合物C(15)H(12)FN中的吲哚N-H氢不显示经典氢键。相反,它与相邻吲哚的π体系形成相互作用,从而沿[001]方向形成弱相互作用链。

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A facile regiocontrol in the palladium-catalyzed annulation of fluorine-containing internal alkynes with variously substituted 2-iodoanilines: a new regioselective synthesis of 2- or 3-fluoroalkylated indole derivatives.钯催化含氟内炔与各种取代的2-碘苯胺环化反应中的简便区域控制:2-或3-氟烷基化吲哚衍生物的一种新的区域选择性合成方法。
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J Med Chem. 1986 Mar;29(3):333-41. doi: 10.1021/jm00153a006.