Department of Neuropathology, National Institute of Mental Health and Neurosciences, Hosur Road, Bangalore, Karnataka, 560 029, India.
Brain Tumor Pathol. 2012 Jan;29(1):25-30. doi: 10.1007/s10014-011-0059-8. Epub 2011 Aug 12.
Myxopapillary ependymoma (MPE), which is a benign histological subtype of ependymoma, is found predominantly in the cauda equina region. It occurs rarely in the brain and mostly as a metastatic deposit from a spinal lesion. The occurrence of primary intracranial MPE is exceptional, with only 11 cases reported to date. We report an additional case of intracranial MPE, which is the third reported case in the fourth ventricle. The tumor manifested in a 50-year-old lady, who presented with features of raised intracranial pressure. A gross total resection of the tumor was achieved. Histologically, the tumor had characteristic features of MPE with focal metaplastic cartilaginous deposit. On further evaluation, there was no evidence of a primary tumor in the spinal cord. Intracranial MPE needs further evaluation by craniospinal MRI to exclude an unrecognized primary in the spinal region, which could warrant surgical attention.
粘液性乳头状室管膜瘤（MPE）是室管膜瘤的一种良性组织学亚型，主要发生在马尾神经区。它在脑内很少见，主要是脊柱病变的转移灶。原发性颅内 MPE 极为罕见，迄今为止仅报告了 11 例。我们报告了另一个颅内 MPE 的病例，这是第四脑室的第三个报告病例。该肿瘤发生在一位 50 岁的女性，表现为颅内压升高的特征。肿瘤实现了大体全切除。组织学上，肿瘤具有 MPE 的特征性特征，伴有局灶性化生软骨沉积。进一步评估后，脊髓内没有原发性肿瘤的证据。颅内 MPE 需要进一步行颅脊髓 MRI 检查，以排除脊柱区域未被识别的原发性肿瘤，这可能需要手术治疗。
