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牙瘤的临床与组织病理学研究:文献综述及160例病例报告

Clinical and histopathological investigation of odontomas: review of the literature and presentation of 160 cases.

作者信息

Soluk Tekkesin Merva, Pehlivan Sevim, Olgac Vakur, Aksakallı Nihan, Alatli Canan

机构信息

Department of Tumor Pathology, Institute of Oncology, Istanbul University, Istanbul, Turkey.

出版信息

J Oral Maxillofac Surg. 2012 Jun;70(6):1358-61. doi: 10.1016/j.joms.2011.05.024. Epub 2011 Aug 15.

DOI:10.1016/j.joms.2011.05.024
PMID:21840103
Abstract

PURPOSE

The purpose of the present study was to evaluate the clinical and histopathologic aspects of different types of odontomas.

MATERIALS AND METHODS

One hundred sixty odontoma cases sent to the Institute of Oncology, Department of Tumor Pathology, Istanbul University from 1971 through 2010 were investigated. These tumors were compared by age of patient, gender of patient, localization, histopathologic type, clinical diagnosis, and clinical and microscopic features.

RESULTS

Odontomas were classified histopathologically as complex, compound, or mixed. Of all investigated cases, 99 were complex, 57 were compound, and 4 were mixed odontomas. The mean age at diagnosis was 27.9 years, and odontomas were diagnosed most frequently at 10 to 19 years of age.

CONCLUSIONS

From the perspective of community health, the presence of odontomas within the jaws is important because these constitute 21% to 67% of all odontogenic tumors. The present study showed 2 interesting findings that differed from previous studies. These are the lower incidence rate of odontomas within the category of odontogenic tumors and the higher incidence of complex odontomas over compound odontomas.

摘要

目的

本研究的目的是评估不同类型牙瘤的临床和组织病理学特征。

材料与方法

对1971年至2010年间送至伊斯坦布尔大学肿瘤研究所肿瘤病理学系的160例牙瘤病例进行了调查。对这些肿瘤按照患者年龄、性别、部位、组织病理学类型、临床诊断以及临床和显微镜特征进行了比较。

结果

牙瘤在组织病理学上分为复杂型、复合型或混合型。在所有调查病例中,99例为复杂型,57例为复合型,4例为混合型牙瘤。诊断时的平均年龄为27.9岁,牙瘤最常发生于10至19岁年龄段。

结论

从社区健康的角度来看,颌骨内牙瘤的存在很重要,因为它们占所有牙源性肿瘤的21%至67%。本研究显示了两个与以往研究不同的有趣发现。这就是牙瘤在牙源性肿瘤类别中的发病率较低以及复杂型牙瘤的发病率高于复合型牙瘤。

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