Watanabe Satoshi, Takato Hazuki, Waseda Yuko, Tokuda Akira, Katayama Nobuyuki, Kondo Yukio, Fujimura Masaki, Nakao Shinji
Respiratory Medicine, Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Sciences, Japan.
Intern Med. 2011;50(16):1733-6. doi: 10.2169/internalmedicine.50.5329. Epub 2011 Aug 15.
We report on a 73-year-old man with systemic lymphadenopathy and chest computed tomography (CT) findings of bilateral diffuse ground-glass opacities and interlobular septal thickening. He also had pulmonary arterial hypertension (PAH). Several lymph node biopsies were attempted, without a definitive diagnosis. A thoracoscopic lung biopsy was performed, and the specimen was diagnosed as peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS). Lymphoma cells had invaded lung vessels, resulting in PAH. We should include pulmonary lymphoma in the differential diagnosis of patients with PAH and chest CT findings of diffuse ground-glass opacities and interlobular septal thickening.
我们报告了一名73岁男性，有全身淋巴结肿大，胸部计算机断层扫描（CT）显示双侧弥漫性磨玻璃影和小叶间隔增厚。他还患有肺动脉高压（PAH）。曾多次尝试进行淋巴结活检，但均未明确诊断。遂进行了胸腔镜肺活检，标本被诊断为外周T细胞淋巴瘤，非特殊类型（PTCL-NOS）。淋巴瘤细胞侵犯了肺血管，导致了PAH。对于有PAH且胸部CT表现为弥漫性磨玻璃影和小叶间隔增厚的患者，我们应将肺淋巴瘤纳入鉴别诊断。
