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表现为铺路石样改变的外周T细胞淋巴瘤肺部受累

Pulmonary involvement of peripheral T-cell lymphoma manifesting as crazy paving pattern.

作者信息

Fraser Traci, Nagarur Amulya

机构信息

Department of Internal Medicine, Massachusetts General Hospital, Boston, Massachusetts.

出版信息

Proc (Bayl Univ Med Cent). 2015 Jan;28(1):59-61. doi: 10.1080/08998280.2015.11929189.

Abstract

Crazy paving pattern is a finding on computed tomography of the chest that is characterized by interlobular septal thickening and ground-glass opacities. Though classically associated with pulmonary alveolar proteinosis, the differential diagnosis for this pattern is broad, and initial workup includes bronchoscopy with bronchoalveolar lavage to evaluate for malignancy, diffuse alveolar hemorrhage, pulmonary alveolar proteinosis, infection, and eosinophilic pneumonia. Herein we present an unusual case of peripheral T-cell lymphoma not otherwise specified (PTCL NOS) with pulmonary involvement that demonstrated crazy paving pattern. The diagnosis was confirmed after cytology from bronchoalveolar lavage revealed atypical lymphocytes with an immunologic profile consistent with the patient's known PTCL NOS.

摘要

碎石路样表现是胸部计算机断层扫描的一种表现,其特征为小叶间隔增厚和磨玻璃样影。虽然传统上与肺泡蛋白沉积症相关,但这种表现的鉴别诊断范围很广,初始检查包括支气管镜检查及支气管肺泡灌洗,以评估是否存在恶性肿瘤、弥漫性肺泡出血、肺泡蛋白沉积症、感染和嗜酸性粒细胞性肺炎。在此,我们报告一例罕见的外周T细胞淋巴瘤,非特指型(PTCL NOS)累及肺部,表现为碎石路样表现。支气管肺泡灌洗的细胞学检查显示非典型淋巴细胞,其免疫表型与患者已知的PTCL NOS一致,从而确诊。

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