First Hospital, Jilin University, Changchun 130021, China.
Am J Med Sci. 2011 Nov;342(5):435-7. doi: 10.1097/MAJ.0b013e318229992c.
Granulosa cell tumors (GCTs) are extremely rare tumors and are divided into 2 types: adult (AGCT) and juvenile (JGCT). The JGCTs represent only 5% of all cases. The incidence of ovarian carcinoma diagnosed during pregnancy varies about 0.0179 to 0.11 per 1000 pregnancies.
A 24-year-old woman at 12 weeks and 3 days of pregnancy was admitted to the authors' hospital due to a pelvic mass. Surgical exploration revealed a smooth, solid, mobile and well-encapsulated left ovarian mass. Histological and immunohistochemical findings led to the diagnosis of a well-differentiated JGCT. Pregnancy continued uncomplicated and she delivered a healthy baby girl at 37 weeks gestation. About 9 months after the original diagnosis, the patient showed no evidence of disease.
Treatment options and a review of the literature related to JGCTs are discussed.
颗粒细胞瘤（GCT）是一种非常罕见的肿瘤，可分为两种类型：成人型（AGCT）和幼年型（JGCT）。JGCT 仅占所有病例的 5%。妊娠期间诊断出的卵巢癌的发病率约为每 1000 例妊娠中 0.0179 至 0.11 例。
一名 24 岁的女性，妊娠 12 周零 3 天，因盆腔肿块就诊于作者医院。手术探查显示左侧卵巢有一个光滑、实性、可移动且包膜完整的肿块。组织学和免疫组织化学检查结果提示为分化良好的 JGCT。妊娠过程顺利，患者于 37 周妊娠时分娩了一名健康女婴。最初诊断后约 9 个月，患者未出现疾病迹象。
讨论了 JGCT 相关的治疗选择和文献复习。
