Department of Preventive Medicine and Public Health, Universidad Autónoma de Madrid, Spain.
J Hypertens. 2011 Oct;29(10):1863-70. doi: 10.1097/HJH.0b013e32834ab497.
To estimate the prevalence and incidence of hypertension in a Spanish cohort of people aged at least 65 years with 13 years' follow-up. This is the first study to provide age-adjusted and sex-adjusted incidence rates of hypertension in a Mediterranean-based population aged 65 years or older.
Population-based longitudinal study set in the city of Leganes, Spain. The cross-sectional prevalence of hypertension was estimated using data available for the 1993, 1995, 1999, and 2006 cohorts. The incidence density (incident cases of hypertension/person-years) was calculated for 522 individuals without hypertension at baseline. Individuals were classified as hypertensive if they were taking physician-prescribed medication for hypertension or if their blood pressure was equal to or greater than 140/90 mmHg.
Hypertension prevalence increased progressively with time, from 53.5% in 1993 to 86.2% in 2006. In all four waves, women had a higher prevalence of hypertension than men (P < 0.05). The total incidence density of hypertension was 7.6 [95% confidence interval (CI) 6.6-8.7] cases per 100 person-years of follow-up: 9.0 (95% CI 7.2-11.2) in women and 6.9 (95% CI 5.8-8.3) in men. In all age groups, the incidence density was nonsignificantly higher in women than in men (P > 0.05).
Both the incidence and prevalence of hypertension in this population of people aged at least 65 years were high, and the prevalence increased dramatically over time, especially among women.
估计西班牙至少 65 岁人群中高血压的患病率和发病率,随访时间为 13 年。这是第一项针对年龄在 65 岁或以上的基于地中海人群提供年龄和性别调整后高血压发病率的研究。
这是一项基于人群的纵向研究,设置在西班牙的莱加内斯市。通过对 1993 年、1995 年、1999 年和 2006 年队列中可用的数据,估计高血压的横断面患病率。对 522 名基线时无高血压的个体计算发病率密度(高血压新发病例/人年)。如果个体正在服用医生开具的高血压药物,或血压等于或大于 140/90mmHg,则将其归类为高血压。
高血压患病率随时间推移而逐渐增加,从 1993 年的 53.5%增加到 2006 年的 86.2%。在所有四个波次中,女性高血压患病率均高于男性(P<0.05)。高血压的总发病率密度为 7.6 [95%置信区间(CI)6.6-8.7]例/100 人年的随访:女性为 9.0(95% CI 7.2-11.2),男性为 6.9(95% CI 5.8-8.3)。在所有年龄组中,女性的发病率密度均高于男性,但差异无统计学意义(P>0.05)。
该至少 65 岁人群的高血压发病率和患病率均较高,且患病率随时间显著增加,尤其是女性。